Two Novel Pyrazole Derived Ionic Liquids Based on Chloride and Trichlorostannate Anions: Preparation, Characterization, and Evaluation of Their Catalytic Activity in the Synthesis of 1H-Pyrazolo[1,2-b]phthalazine-5,10-diones

Copper(II) Schiff-Base Complex Modified UiO-66-NH2(Zr) Metal–Organic Framework Catalysts for Knoevenagel Condensation–Michael Addition–Cyclization Reactions

“…Moreover, variation in active methylene compounds, carbonyls, and Michael-donor agents can lead to the production of special intermediates that can perform cycloaddition reactions, producing five- or six-membered nitrogen- or oxygen-containing heterocyclic products. The Knoevenagel condensation–Michael addition–cyclization of an aldehyde, malononitrile, and phthalhydrazide or 4-hydroxycoumarin generates chiral 1 H -pyrazolo­[1,2- b ]­phthalazine-5,10-diones and dihydropyrano­[2,3- c ]­chromenes, respectively. − In addition, they have been regarded as beneficial precursors to many drugs and natural products. , In the presence of transition-metal catalysts, these compounds, which have generated much interest because of their diverse remedial and pharmacological applications, are generated from these reactions. − Regarding numerous catalysts, the performance of these catalytic systems can be restricted by their low activities, harsh reaction conditions, use of unstable solvents, low turnover frequency, and problems related to the separation and reusability of this homogeneous catalyst from the reaction mixture . Moreover, it is worth mentioning that the scope and selectivity of these methods should be improved. ,, Herein, we aim at developing a new catalyst for the synthesis of the chiral 1 H -pyrazolo­[1,2- b ]­phthalazine-5,10-dione and dihydropyrano­[2,3- c ]­chromenes under green conditions.…”