Two novel diorganotin phosphonic diamides: syntheses, crystal structures, spectral properties and in vitro antibacterial studies

Abstract

, respectively. The compounds were characterized by elemental analysis, IR and multinuclear NMR ( 1 H, 13 C, 31 P and 119 Sn) spectroscopy. The crystal structures of the complexes were determined by X-ray single crystal analysis, which revealed that complex 1 has a distorted octahedral geometry and complex 2 has a distorted trigonal bipyramidal structure with non-equivalent chlorine atoms. Preliminary antibacterial tests of the compounds against Gram-positive and -negative bacteria were carried out using the filter paper disk method and chloroamphenicol was used as standard for comparison.

Synthesis, structural characterization, density functional theory calculations and biological evaluation of a new organotin(IV) complex containing N‐isonicotinyl‐N',N″‐diaryl phosphorictriamide as N‐donor ligand

“…aeruginosa and 20 mm for the other tested microorganisms. These results are in keeping with those for other organotin(IV) compounds . The present investigation of antimicrobial screening data reveals that C 1a exhibits similar activity compared to the control drug towards E .…”

Diorganotin(IV) complexes of N-mono-, di- and tri-chloroacetyl, N′,N″-bis(isopropyl) phosphoric triamide

“…So, The cis bond angles deviates slightly from the idealized value, 90 , and the deviation is smaller than the corresponding one found for SnCl 2 (CH 3 The Sn(2) atom is merely penta-coordinated and has a distorted trigonal bipyramidal geometry with the oxygen of the carbonyl group and a chlorine atom in axial sites (Cl(5)eSn(2)eO(4), 171.99 (7) ) and another chlorine and two methyl groups occupying the equatorial plane which is in accordance with previously published results [30]. The low donor strength of carbonyl group gives rise to a considerable distortion of the trigonal-bipyramide around the tin atom toward a monocapped tetrahedron.…”

“…The difference between two axial and equatorial SneCl bonds in 4 is smaller than the corresponding one found for SnCl 2 (CH 3 due to the shorter axial SneO(P) band in the later (2.258(2) Å) [30]. As expected, the Sn(1)eCl bonds are longer than S(2)eCl bonds.…”

“…The two Sn(2)eCl bond lengths lie in the range of the normal covalent radii [34,29] but are not equivalent, that trans to O atom being longer than the other (Sn(2)eCl(6), 2.3854(12) Å, equatorial bond and Sn(2)eCl(5), 2.4136(12) Å, axial bond), as observed for other organotin compounds with the same geometry [30]. The difference between two axial and equatorial SneCl bonds in 4 is smaller than the corresponding one found for SnCl 2 (CH 3 due to the shorter axial SneO(P) band in the later (2.258(2) Å) [30].…”

Ultrasonic‐assisted synthesis and biological evaluation of a nano‐rod diorganotin phosphonic diamide: Precursor for the fabrication of SnP2O7 nano‐structure

“…The coordination chemistry of organotin compounds has become of great interest because of their important applications as anticancer agents, agrochemical fungicides and biocides, as well as catalysts . Synthesis of organotin with phosphoramide ligands by the reaction of Sn(R) n Cl 4‐n ( n = 1–3) (R = Cl, CH 3 , C 6 H 5 ) with various phosphoramides, as well as evaluation of their cytotoxicity against some human cell lines and microbial strains have frequently been studied . Recently, the development of coordination complexes as nano‐structured materials has increased for nanotechnological applications because of their superior physical and chemical properties that cannot be observed in bulk counterparts.…”