2015
DOI: 10.1111/iji.12194
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Two novel 5′ promoter sequences of the MHC class I‐related chain A gene

Abstract: In this study, we have characterized two novel polymorphism of the 5' promoter sequence of MICA gene, MICA-P13 and MICA-P14, by sequence-based typing and cloning.

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“…The promoter regions of the MIC family were thought to be invariant for MICA promoter region and slightly polymorphic for MICB promoter (Eagle et al, 2006) until previous studies described 14 polymorphisms in MICA promoter (Cox et al, 2014;Luo et al, 2014;Laza-Briviesca et al, 2015) and 13 different sequences for MICB promoter region (Cox et al, 2014;Pan et al, 2014).…”
Section: Introductionmentioning
confidence: 99%
“…The promoter regions of the MIC family were thought to be invariant for MICA promoter region and slightly polymorphic for MICB promoter (Eagle et al, 2006) until previous studies described 14 polymorphisms in MICA promoter (Cox et al, 2014;Luo et al, 2014;Laza-Briviesca et al, 2015) and 13 different sequences for MICB promoter region (Cox et al, 2014;Pan et al, 2014).…”
Section: Introductionmentioning
confidence: 99%