Two new sulphated flavonol glucosides from leaves of Malva sylvestris

Nawwar, Mahmoud A.M.; Dein, Alei El; Sherbeiny, A. E. A. El; El-Ansari, Mohamed A.; Sissi, H. I. El

doi:10.1016/0031-9422(77)83042-2

Cited by 17 publications

(3 citation statements)

References 3 publications

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“…Analytical data on the chemical and total phenolic contents of this species are very rare. However, previous chemical investigations have shown the presence of anthocyanins, flavones, flavonols, ferulic acid, hydroxycinnamic acids, sterols, sesquiterpenes, mono and diterpenes in leaves and stems of M. sylvestris L. (Nawwar et al, 1977;Nicoletti et al, 1989;Mas et al, 1999;Cutillo et al, 2006;Quave et al, 2008b). Therefore, it is important to study the antioxidant and antimicrobial activity of edible parts (leaves and stems) and non edible parts (flowers and seeds) from mallow (M. sylvestris L.), a green wild plant that is much consumed and appreciated for its culinary and medicinal virtues in *Corresponding author.…”

Section: Introductionmentioning

confidence: 93%

Antioxidant activity, phenolic and flavonoid content in leaves, flowers, stems and seeds of mallow (Malva sylvestris L.) from North Western of Algeria

Beghdad¹,

Benammar²,

Bensalah³

et al. 2014

Afr. J. Biotechnol.

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The nutraceutical composition (phenolics and flavonoids) of all leaves, flowers, stems and seeds of mallow, Malva sylvestris L., as well as their antioxidant properties were studied using in vitro methods: ferric reducing antioxidant power (FRAP) assay, by scavenging of 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical and total antioxidant capacity (TAC) based on the reduction of molybdenum (VI) to molybdenum (V). Results show that all extracts possessed concentration-dependant antioxidant activity. Leaf extracts have a highest amount of total phenolics with 24.123 ± 0.718 mg GAE/g, and total flavonoids with 0.694 ± 0.017 mg RE/100 g. However, the seed extracts presented the lowest amount in the two assays used. In addition, the AcOEt (EC 50 = 3.10 mg/ml) fraction showed the highest value of antioxidant activities for almost all parts of leaves.

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Section: Introductionmentioning

confidence: 93%

Antioxidant activity, phenolic and flavonoid content in leaves, flowers, stems and seeds of mallow (Malva sylvestris L.) from North Western of Algeria

Beghdad¹,

Benammar²,

Bensalah³

et al. 2014

Afr. J. Biotechnol.

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“…In a study involving the nutraceutical potential of its extracts, the total flavonoids were 210.8, 46.6, 25.4 and 143.4 mg/g in the leaves, flowers, immature fruits and flowered stems, respectively. [10] In the leaves, gossypetin 3-sulphate-8-O-b-dglucoside (gossypin) and hypolaetin 3′-sulphate were identified as the major constituents, followed by 3 [20,104,105] Flavonoids have been found mostly in the flowers, especially anthocyanins such as malvidin 3,5-diglucoside (malvin), which occurs exclusively in the flavylium cationic form. [21,[106][107][108][109][110][111][112] Malvidin 3-O-glucoside (oenin); malvidin; delphinidin 3-O-glucoside; malvidin 3-O-(6″-Omalonylglucoside)-5-O-glucoside; delphinidin; malvidin chloride; genistein; myricetin; and derivatives of apigenin, quercetin and kaempferol have also been found in the flowers, with total anthocyanin content ranging from 0.42 to 7.3% of dry matter.…”

Section: Amino Acids/protein Derivativesmentioning

confidence: 99%

Ethnobotanical and scientific aspects of Malva sylvestris L.: a millennial herbal medicine

Gasparetto

Martins

Hayashi

et al. 2011

Journal of Pharmacy and Pharmacology

179

101

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Objectives Malva sylvestris L., known as common mallow, is native to Europe, North Africa and Asia. In the Mediterranean region, this species has a long history of use as food, and due to its therapeutic relevance, some parts of this plant have been employed in traditional and ethnoveterinary medicines. The leaves in particular have been reported to have potent anti-inflammatory, antioxidant, anti-complementary, anticancer and skin tissue integrity activity. Additionally, an anti-ulcerogenic effect was recently proven, demonstrating that the aqueous extract was more effective than cimetidine, a potent medicine used to treat gastric ulcers. Due to its wide use and medicinal importance, many studies have been conducted; however, the information in the literature is very extensive and disseminated, making it difficult to use. Key findings A complete review involving the ethnobotanical and scientific aspects of M. sylvestris has been made. The research has provided evidence that M. sylvestris has potential use as a medicinal plant and has highlighted a need for more studies involving clinical and toxicological aspects of its use. Summary This review can contribute to the field with its historical context, and by describing the progress made, new ideas for researchers can arise.

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“…Total phenolic compounds were identified in leaves (386.5 mg g −1 ), flowering stems (317.0 mg g −1 ), flowers (258.7 mg g −1 ), and immature fruits (56.8 mg g −1 ) [143]. The primary components of the leaves were identified as gossypetin 3-sulphate-8-O-β-D-glucoside (gossypin) and hypolaetin 3 ′ -sulphate, followed by isoscutellarein 8-O-β-D-glucuronpyranoside, hypolaetin 8-O-β-D-glucuronopyranoside, 3-O-β-D-glucopyranosyl-8-O-β-D-glucuronopyranoside, and hypolaetin 4 ′ -methyl ether 8-O-β-D-glucuronopyranoside [145,235,236]. Anthocyanins like malvin (malvidin 3,5-glucoside), found only in flavylium cationic form, were mostly identified in flowers [237][238][239][240].…”

Section: Bioactive Phytochemicalsmentioning

confidence: 99%

Nutraceutical Aspects of Selected Wild Edible Plants of the Italian Central Apennines

Fantasma,

Samukha,

Saviano

et al. 2024

Nutraceuticals

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All over the world, wild edible plants are an essential source of chemical components that justify their use in folk medicine. The aim of this review is to document and summarize the knowledge of ten wild plants analyzed in a previous study for their ethnomedical significance. Achillea millefolium, Borago officinalis, Foeniculum vulgare, Gentiana lutea, Juniperus communis, Laurus nobilis, Malva sylvestris, Satureja montana, Silybum marianum and Urtica dioica were the subjects of our study. They are commonly found in the central Italian Apennines and the Mediterranean basin. Phytochemicals contained in wild plants, such as phenols, polyphenols, flavonoids, condensed tannins, carotenoids, etc., are receiving increasing attention, as they exert a wide range of biological activities with resulting benefits for human health. Based on the 353 studies we reviewed, we focused our study on the following: (a) the ethnobotanical practices and bioactive phytochemicals; (b) the composition of polyphenols and their role as antioxidants; (c) the methodologies commonly used to assess antioxidant activity; (d) the most advanced spectroscopic and spectrometric techniques used to visualize and characterize all components (metabolomic fingerprinting). The potential of pure compounds and extracts to be used as nutraceuticals has also been highlighted through a supposed mechanism of action.

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Two new sulphated flavonol glucosides from leaves of Malva sylvestris

Cited by 17 publications

References 3 publications

Antioxidant activity, phenolic and flavonoid content in leaves, flowers, stems and seeds of mallow (Malva sylvestris L.) from North Western of Algeria

Antioxidant activity, phenolic and flavonoid content in leaves, flowers, stems and seeds of mallow (Malva sylvestris L.) from North Western of Algeria

Ethnobotanical and scientific aspects of Malva sylvestris L.: a millennial herbal medicine

Nutraceutical Aspects of Selected Wild Edible Plants of the Italian Central Apennines

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