Two new pentacyclic triterpenoids from the stems of Manihot esculenta

Yamei, Pan; Zou, Tao; Chen, Yongju; Chen, Jianyong; Ding, Xiao; Hao, Xiao‐Jiang; He, Hongping

doi:10.1016/j.phytol.2015.04.018

Cited by 6 publications

(3 citation statements)

References 23 publications

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“…Although there is a lack of research on their mechanism of action, the study proposed that the unsaturation of the chemical structure may significantly contribute to their anti-cancer property. 88…”

Section: Discussionmentioning

confidence: 99%

“…Worthy of note that both compounds are cis-trans isomers of each other, which have demonstrated moderate anti-cancer activity where the configuration of the double bond may play a significant role in its cytotoxic activity. 88 Recently, silica gel column was employed to isolate and identify two new terpenoids from ethanolic cassava stem extract, namely sporogen AO-2, a sesquiterpene, and thecacorin C, a diterpene. Both compounds were found to display modest anti-bacterial activity upon examination.…”

Section: Phytochemistrymentioning

confidence: 99%

“…Chemical Components Summary of Cassava. 19,22,23,25,31,33,34,38,40,45,[47][48][49]53,88,89,93,[95][96][97][98] Phytochemical groups Components Plant part Extraction methods/solvent used References…”

Section: Phytochemistrymentioning

confidence: 99%

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Cassava (Manihot esculenta Crantz): A Systematic Review for the Pharmacological Activities, Traditional Uses, Nutritional Values, and Phytochemistry

Mohidin,

Moshawih,

Hermansyah

et al. 2023

J Evid Based Complementary Altern Med

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Cassava ( Manihot esculenta Crantz) is considered one of the essential tuber crops, serving as a dietary staple food for various populations. This systematic review provides a comprehensive summary of the nutritional and therapeutic properties of cassava, which is an important dietary staple and traditional medicine. The review aims to evaluate and summarize the phytochemical components of cassava and their association with pharmacological activities, traditional uses, and nutritional importance in global food crises. To collect all relevant information, electronic databases; Cochrane Library, PubMed, Scopus, Web of Science, Google Scholar, and Preprint Platforms were searched for studies on cassava from inception until October 2022. A total of 1582 studies were screened, while only 34 were included in this review. The results of the review indicate that cassava has diverse pharmacological activities, including anti-bacterial, anti-cancer, anti-diabetic, anti-diarrheal, anti-inflammatory, hypocholesterolemic effects, and wound healing properties. However, more studies that aim to isolate the phytochemicals in cassava extracts and evaluate their pharmacological property are necessary to further validate their medical and nutritional values.

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Section: Discussionmentioning

confidence: 99%

Section: Phytochemistrymentioning

confidence: 99%