Two Newm-Cresol Derivatives and a New Terpene Alcohol from Peppermint Oil

Synthesis of furyl analogues of acyclic monoterpenes

“…However, in our experiments, a three-step procedure was adopted for this purpose. 15 First, alcohols 2 were reacted with PBr 3 to give 2-(5-bromo-3-methylpent-3-enyl)-furan or 2-(5-bromo-3-methylpent-3-enyl)-5-methylfuran and then, without isolation, they were treated with potassium acetate to furnish a stereoisomeric mixture of the acetate 3. Geraniol and nerol analogues 4 were obtained by an alkaline hydrolysis of acetates 3 in 42% yield (overall).…”