Two New Chromones from Cassia auriculata and Their Antiviral Activity

Liu, Xiaoshan; Zheng, Jun-Na; Shen, Siyu; Xiong, Wen; Li, S. H.; Ma, Xiaodong; Li, Yin-Ke; Zhou, Min; Gong, Daping; Hu, Qiu‐Fen; Dong, Miao; Zhang, Fengmei

doi:10.1007/s10600-023-04025-4

Cited by 5 publications

(2 citation statements)

References 23 publications

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“…In another study involving the same species, Liu and co-workers investigated the stem bark of C. auriculata and isolated two new chromones (60 and 61, Figure 10) along with four known ones. 46 The new compounds were elucidated by means of spectroscopic methods, and their structure was established as 2-(2-(furan-2-yl)-2-oxoethyl)-6-methoxy-8-(2-oxopropyl)chromone (60) and 2-(2-(furan-2-yl)-2-oxoethyl)-5-methoxy-8-(2-oxopropyl)-chromone (61). As the extract from C. auriculata, and certain chromones belonging to the genus Cassia exhibit potential antiviral activities, compounds 60 and 61 were evaluated for their antitobacco mosaic virus (TMV) and antirotavirus activities.…”

Section: Aquilaria Sinensismentioning

confidence: 99%

“…In another study involving the same species, Liu and co-workers investigated the stem bark of C. auriculata and isolated two new chromones ( 60 and 61 , Figure ) along with four known ones . The new compounds were elucidated by means of spectroscopic methods, and their structure was established as 2-(2-(furan-2-yl)-2-oxoethyl)-6-methoxy-8-(2-oxopropyl)-chromone ( 60 ) and 2-(2-(furan-2-yl)-2-oxoethyl)-5-methoxy-8-(2-oxopropyl)-chromone ( 61 ).…”

Section: Chromones and Chromanones From Natural Sourcesmentioning

confidence: 99%

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Biological and Medicinal Properties of Natural Chromones and Chromanones

Gaspar,

Garrido,

Borges

et al. 2024

ACS Omega

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Emerging threats to human health require a concerted effort to search for new treatment therapies. One of the biggest challenges is finding medicines with few or no side effects. Natural products have historically contributed to major advances in the field of pharmacotherapy, as they offer special characteristics compared to conventional synthetic molecules. Interest in natural products is being revitalized, in a continuous search for lead structures that can be used as models for the development of new medicines by the pharmaceutical industry. Chromone and chromanones are recognized as privileged structures and useful templates for the design of diversified therapeutic molecules with potential pharmacological interest. Chromones and chromanones are widely distributed in plants and fungi, and significant biological activities, namely antioxidant, anti-inflammatory, antimicrobial, antiviral, etc., have been reported for these compounds, suggesting their potential as lead drug candidates. This review aims to update the literature published over the last 6 years (2018–2023) regarding the natural occurrence and biological activity of chromones and chromanones, highlighting the recent findings and the perspectives that they hold for future research and applications namely in health, cosmetic, and food industries.

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Section: Aquilaria Sinensismentioning

confidence: 99%

Section: Chromones and Chromanones From Natural Sourcesmentioning

confidence: 99%