Two New Chromeno[3,2-c]Pyridine Derivatives from the Whole Plants of Thalictrum finetii and Their Antirotavirus Activity

Hu, Qiu‐Fen; Zhang, Lingfang; Liu, Mingxin; Cai, Bing-Biao; Li, Yong; Zhou, Tao; Li, Man-Fei; Wang, Hua-Shun; Xu, Yongnan; Kong, Wei-Song; Zhou, Min; Yang, Guangyu; Jiang, Ju‐Xing

doi:10.1007/s10600-022-03720-y

Cited by 5 publications

(2 citation statements)

References 15 publications

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“…In the new compounds review, four studies reported new molecular structures derived from the alkaloids class, totaling nine new molecules, including two new chromeno[3,2-c] pyridine alkaloids from Thalictrum scabrifolium, three new anti-rotavirus quinoline alkaloids from the whole plant of Thalictrum glandulossissimun, two new chromeno[3,2-c] pyridine derivates from Thalictrum finetii, and two new anti-tobacco mosaic virus alkaloids from Thalictrum microgynum [43][44][45][46][47].…”

Section: Garciniamentioning

confidence: 99%

New Compounds from Terrestrial Plants: A Perspective View

Oliveira,

Kohatsu,

Hufnagel

et al. 2024

Compounds

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In an era where the search for innovative drug leads faces challenges, our study pivots towards exploring the untapped potential of plant-derived compounds, focusing on the period of 2021 to 2022. We assess the classes of compounds these new structures belong to; the plants and families these compounds belong to; and the degree of novelty of the compound compared with already-known structures. The review was conducted following the Preferred Reporting Items for Systematics Reviews and Meta-Analyses (PRISMA) statement checklist for the guided reporting of systematic reviews. A total of 464 articles were selected for the new compounds of natural origin survey. We included 117 complete articles in this review and reported approximately 109 new structures elucidated during the years 2021 and 2022. Many of the compounds showed small structural variations in relation to already-known molecules. For some, however, this small modification was decisive for the biological activity reported, demonstrating the importance of descriptive phytochemical studies.

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Section: Garciniamentioning

confidence: 99%

New Compounds from Terrestrial Plants: A Perspective View

Oliveira,

Kohatsu,

Hufnagel

et al. 2024

Compounds

View full text Add to dashboard Cite

show abstract

“…In the new compounds review, 4 studies reported new molecular structures derived from the alkaloids class, totaling nine new molecules, including two new chromeno[3,2-c] pyridine alkaloids from Thalictrum scabrifolium, three new anti-rotavirus quinoline alkaloids from the whole plant of Thalictrum glandulossissimun, two new chromeno[3,2-c] pyridine derivates from Thalictrum finetii, and two new anti-tobacco mosaic virus alkaloids from Thalictrum microgynum [43][44][45][46][47].…”

Section: Thalictrummentioning

confidence: 99%

New Compounds from Plants: A Perspective View

Oliveira,

Kohatsu,

Hufnagel

et al. 2023

Preprint

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In view of the diminishing contribution of natural products from plants to the discovery of new chemical structures, the aim of this study was to compile the articles from 2021 to 2022, assessing: (1) which classes of compounds these new structures belong to; (2) which plants and families these compounds belong to and (3) assessing the degree of novelty of the compound with an already known structure. The review was elaborate following the Preferred Reporting Items for System-atics Reviews and Meta-analyses (PRISMA) statement checklist for guide reporting of systematic reviews. A total of 464 articles were selected for the new compounds of natural origin survey. We included 117 complete articles in this review and reported approximately 109 new structures elucidated during the years 2021 and 2022. Many of the compounds showed small structural var-iations in relation to already known molecules. For some, however, this small modification was decisive for the biological activity reported, demonstrating the importance of descriptive phytochemical studies.

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