Two New Acylated Flavonol Glycosides from the Seeds of Lepidium sativum

Fan, Qing-Lu; Zhu, Yindi; Huang, Weichao; Qi, Yun; Guo, Baolin

doi:10.3390/molecules190811341

Cited by 19 publications

(19 citation statements)

References 19 publications

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“…O-α-L rhamnopyranoside was identified by Fan et al [7]. However, while the same acylation was present in the Algerian variety, quercetin was replaced by a kaempferol.…”

Section: Discussionmentioning

confidence: 64%

“…The differential activities of flavonoids could depend on the solvent used for extraction and on the position of substituents in the flavonoid nucleus. These differences in substituents give rise to the major bioactive compounds such as quercetine, kampferol and their glycosides which are present in Lepidium sativum seeds [7,[15][16][17].…”

Section: Discussionmentioning

confidence: 99%

“…Several studies have been done on Lepidium sativum seeds. Recently, two new acylated kaempferol and quercetin compounds isolated from the seeds of Lepidium sativum [7]. In this study, the phytochemical composition, antioxidant properties and antibacterial activities of n-butanol extract of Lepidium sativum seeds were investigated.…”

Section: Introductionmentioning

confidence: 99%

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Chemical composition and biological activities of n-butanol extract of <i>Lepidium sativum L</i> (Brassicaceae) seed

Ait-yahia¹,

Perreau²,

Bouzroura³

et al. 2018

Trop. J. Pharm Res

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“…O-α-L rhamnopyranoside was identified by Fan et al [7]. However, while the same acylation was present in the Algerian variety, quercetin was replaced by a kaempferol.…”

Section: Discussionmentioning

confidence: 64%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Chemical composition and biological activities of n-butanol extract of <i>Lepidium sativum L</i> (Brassicaceae) seed

Ait-yahia¹,

Perreau²,

Bouzroura³

et al. 2018

Trop. J. Pharm Res

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“…Its main fatty acids are oleic acid (30%) and α-linolenic acid (32%) representing the n-3 group. Cress seeds also contain a high level of polyphenols and are a source of bioactive glycosides [15,19]. It has been found that the isoflavone glycoside isolated from L. sativum seeds can improve liver function and the serum lipid profile.…”

Section: Introductionmentioning

confidence: 99%

Assessment of the Properties of Rapeseed Oil Enriched with Oils Characterized by High Content of α-linolenic Acid

et al. 2019

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Functional foods include cold-pressed oils, which are a rich source of antioxidants and bioactive n-3 and n-6 polyunsaturated fatty acids. The aim of this study was to assess the quality of rapeseed oils supplemented with Spanish sage and cress oils. Seven oil mixtures consisting of 70% of rapeseed oil and 30% of sage and/or cress oil were prepared for the analyses. The oil mixtures were analyzed to determine their acid value, peroxide value, oxidative stability, and fatty acid composition. In terms of the acid value and the peroxide value, all mixtures met the requirements for cold-pressed vegetable oils. The enrichment of the rapeseed oil with α-linolenic acid-rich fats resulted in a substantially lower ratio of n-6 to n-3 acids in the mixtures than in the rapeseed oil. The mixture of the rapeseed oil with the sage and cress oils in a ratio of 70:10:20 exhibited higher oxidative stability than the raw materials used for enrichment and a nearly 20% α-linolenic acid content. The oils proposed in this study can improve the ratio of n-6:n-3 acids in modern diets. Additionally, mixing the cress seed oils with rapeseed oil and chia oil resulted in a reduction in the content of erucic acid in the finished product. This finding indicates that cress seeds, despite their high content of erucic acid, can be used as food components. The production of products with a positive effect on human health is one of the most important factors in the sustainable development of agriculture.

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“…This effect appears to be related to the increased urinary elimination of sodium, potassium, and chlorides (Maghrani et al, 2005 ; Table 5 ). Recently, two new glycosides isolated from seeds of L. sativum were shown to have an anti-inflammatory potential (Fan et al, 2014 ). Another member of the Lepidium genus is Lepidium latifolium , commonly known as broadleaved pepper weed.…”

Section: Herbs and Spices Less Commonly Used For Treatment Of Hypertementioning

confidence: 99%

Anti-Hypertensive Herbs and Their Mechanisms of Action: Part II

2016

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Traditional medicine has a history extending back to thousands of years, and during the intervening time, man has identified the healing properties of a very broad range of plants. Globally, the use of herbal therapies to treat and manage cardiovascular disease (CVD) is on the rise. This is the second part of our comprehensive review where we discuss the mechanisms of plants and herbs used for the treatment and management of high blood pressure. Similar to the first part, PubMed and ScienceDirect databases were utilized, and the following keywords and phrases were used as inclusion criteria: hypertension, high blood pressure, herbal medicine, complementary and alternative medicine, endothelial cells, nitric oxide (NO), vascular smooth muscle cell (VSMC) proliferation, hydrogen sulfide, nuclear factor kappa-B (NF-κB), oxidative stress, and epigenetics/epigenomics. Each of the aforementioned keywords was co-joined with plant or herb in question, and where possible with its constituent molecule(s). This part deals in particular with plants that are used, albeit less frequently, for the treatment and management of hypertension. We then discuss the interplay between herbs/prescription drugs and herbs/epigenetics in the context of this disease. The review then concludes with a recommendation for more rigorous, well-developed clinical trials to concretely determine the beneficial impact of herbs and plants on hypertension and a disease-free living.

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Two New Acylated Flavonol Glycosides from the Seeds of Lepidium sativum

Abstract: Two new acylated flavonol glycosides named kaempferol

Cited by 19 publications

References 19 publications

Chemical composition and biological activities of n-butanol extract of <i>Lepidium sativum L</i> (Brassicaceae) seed

Chemical composition and biological activities of n-butanol extract of <i>Lepidium sativum L</i> (Brassicaceae) seed

Assessment of the Properties of Rapeseed Oil Enriched with Oils Characterized by High Content of α-linolenic Acid

Anti-Hypertensive Herbs and Their Mechanisms of Action: Part II

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