Two New 5-Oxomilbemycins Possessing an Unusual 3,27-Epoxy Bond from the Genetically Engineered Strain Streptomyces bingchenggensis BCJ60

Hao, Zhikui; Li, Jiansong; Wang, Jidong; Xiang, Wensheng; Wang, Haiyan

doi:10.1007/s10600-021-03339-5

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Structures and Nematicidal Activity1

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2023

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“…They possessed potent nematicidal capacities gainst B. xylophilus , comparable to that of milbemycins A3/A4, a commercial pesticide. 18–23 Compound 35 , an analog of nemadectins and milbemycins, was isolated from Streptomyces microflavus neau3. It possessed activity against C. elegans , with an LC 50 value of 15.4 ± 1.0 μg mL −1 .…”

Section: Structures and Nematicidal Activitymentioning

confidence: 99%