Two Mixed-ligand Coordination Polymers: Treatment Activity on Acute Oral Mucositis during Orthodontic Process by Reducing Inflammatory Response

Ren, Jiajie; Du, Zhen; Jiang, Lin; Chen, Zhiyuan; Feng, Xiaodong

doi:10.5650/jos.ess20087

Cited by 2 publications

(2 citation statements)

References 19 publications

(1 reference statement)

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“…The clinical manifestations of OM are erythematous, erosive, and ulcerative lesions of the oral mucosa, and it is exacerbated by tissue damage produced by sharpened teeth, bruxism, orthodontics appliances, food scraps, and other oral irritants. Thus, subsequent ulcerations become a free entryway for microorganisms ( 6 , 7 ). On another side, OM represents a significant problem for oncological patients, because is one of the most common adverse effects of chemo/radiotherapy for oral cancer ( 8 ).…”

Section: Introductionmentioning

confidence: 99%

Chitosan for the treatment of inflammation of the oral mucosa: A systematic review

Zúñiga-López,

Márquez-Pérez,

Argueta-Figueroa

et al. 2024

Med Oral

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Background Chitosan is a cheap, accessible, nontoxic, biocompatible, and biodegradable compound. Also, this polysaccharide possesses antibacterial and anti-inflammatory properties. Consequently, a wide range of chitosan applications in the dentistry field has been explored. This work aimed to conduct a systematic review to address the clinical efficacy of chitosan for the treatment of oral mucositis. Material and Methods The design of the included studies were observational studies, randomized clinical trials (RCT), and non-randomized clinical trials (non-RCT), whereas, a series of cases, in vivo , and in vitro studies were excluded. The search was performed in PubMed, Web of Science, Scopus, Dentistry and Oral Sciences Source, and ClinicalTrials. Gray literature was searched at Google Scholar. Relevant data from all included studies were recorded. The risk of bias (using RoB 2) and the quality (using Grading of Recommendations Assessment, Development, and Evaluation, GRADE) assessments were carried out. Results From the 8413 records screened, 5 clinical trials fully met the eligibility criteria, which comprised a total of 192 participants suffering oral lesions and pain related to oral mucositis. 100% of the included studies exhibited a high risk of bias. The quality of the studies was between low and very low. Conclusions The results of the included studies suggest that chitosan can diminish pain and improve the healing of ulcers in oral mucositis. However, there is no conclusive evidence of chitosan as a superior treatment for oral mucositis compared with other current therapies. Key words: Dentistry, chitosan, inflammation, oral disease, wound healing.

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Section: Introductionmentioning

confidence: 99%

Chitosan for the treatment of inflammation of the oral mucosa: A systematic review

Zúñiga-López,

Márquez-Pérez,

Argueta-Figueroa

et al. 2024

Med Oral

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“…Polymers have been extensively used as orthodontic materials due to their appropriate mechanical properties and esthetic quality. Orthodontic polymers could be classified into adhesives, brackets, and elastomeric modules and chains [ 21 , 22 , 23 , 24 ]. Various types of orthodontic polymers are commercially available, such as polycarbonate, polyurethane, polyethylene, polyamides, and polymethyl methacrylate, etc.…”

Section: Introductionmentioning

confidence: 99%

A Review on Current Trends of Polymers in Orthodontics: BPA-Free and Smart Materials

et al. 2021

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Polymeric materials have always established an edge over other classes of materials due to their potential applications in various fields of biomedical engineering. Orthodontics is an emerging field in which polymers have attracted the enormous attention of researchers. In particular, thermoplastic materials have a great future utility in orthodontics, both as aligners and as retainer appliances. In recent years, the use of polycarbonate brackets and base monomers bisphenol A glycerolate dimethacrylate (bis-GMA) has been associated with the potential release of bisphenol A (BPA) in the oral environment. BPA is a toxic compound that acts as an endocrine disruptor that can affect human health. Therefore, there is a continuous search for non-BPA materials with satisfactory mechanical properties and an esthetic appearance as an alternative to polycarbonate brackets and conventional bis-GMA compounds. This study aims to review the recent developments of BPA-free monomers in the application of resin dental composites and adhesives. The most promising polymeric smart materials are also discussed for their relevance to future orthodontic applications.

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Two Mixed-ligand Coordination Polymers: Treatment Activity on Acute Oral Mucositis during Orthodontic Process by Reducing Inflammatory Response

Cited by 2 publications

References 19 publications

Chitosan for the treatment of inflammation of the oral mucosa: A systematic review

Chitosan for the treatment of inflammation of the oral mucosa: A systematic review

A Review on Current Trends of Polymers in Orthodontics: BPA-Free and Smart Materials

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