Abstract:Two-level lumbar disc replacement improves spinal function while preserving its mobility. But this procedure is fraught with risks and must be carried out by a highly-experienced team. A longer follow-up is needed to evaluate the sustainability of the results and to detect any adjacent segment disease. The French National Authority for Health (HAS) has recommended against two-level lumbar disc replacement, so it no longer can be performed in France.
“…Despite good results for single-level LDA, there is evidence to suggest that the two-level arthroplasty constructs have comparatively poorer outcomes and have an increase in the rate of complications compared to the two-level fusions [94117118]. However, conflicting data exists with some authors reporting good outcomes with two-level LDA [119] and outcomes comparable to single-level LDA [117120121], and thus calling into question the role of design and constraint of the implant itself [122123].…”
Section: Multiple-level Lda and Hybrid Lda/fusion Techniquesmentioning
Lumbar degenerative disc disease is extremely common. Current evidence supports surgery in carefully selected patients who have failed non-operative treatment and do not exhibit any substantial psychosocial overlay. Fusion surgery employing the correct grafting and stabilization techniques has long-term results demonstrating successful clinical outcomes. However, the best approach for fusion remains debatable. There is some evidence supporting the more complex, technically demanding and higher risk interbody fusion techniques for the younger, active patients or patients with a higher risk of non-union. Lumbar disc arthroplasty and hybrid techniques are still relatively novel procedures despite promising short-term and mid-term outcomes. Long-term studies demonstrating superiority over fusion are required before these techniques may be recommended to replace fusion as the gold standard. Novel stem cell approaches combined with tissue engineering therapies continue to be developed in expectation of improving clinical outcomes. Results with appropriate follow-up are not yet available to indicate if such techniques are safe, cost-effective and reliable in the long-term.
“…Despite good results for single-level LDA, there is evidence to suggest that the two-level arthroplasty constructs have comparatively poorer outcomes and have an increase in the rate of complications compared to the two-level fusions [94117118]. However, conflicting data exists with some authors reporting good outcomes with two-level LDA [119] and outcomes comparable to single-level LDA [117120121], and thus calling into question the role of design and constraint of the implant itself [122123].…”
Section: Multiple-level Lda and Hybrid Lda/fusion Techniquesmentioning
Lumbar degenerative disc disease is extremely common. Current evidence supports surgery in carefully selected patients who have failed non-operative treatment and do not exhibit any substantial psychosocial overlay. Fusion surgery employing the correct grafting and stabilization techniques has long-term results demonstrating successful clinical outcomes. However, the best approach for fusion remains debatable. There is some evidence supporting the more complex, technically demanding and higher risk interbody fusion techniques for the younger, active patients or patients with a higher risk of non-union. Lumbar disc arthroplasty and hybrid techniques are still relatively novel procedures despite promising short-term and mid-term outcomes. Long-term studies demonstrating superiority over fusion are required before these techniques may be recommended to replace fusion as the gold standard. Novel stem cell approaches combined with tissue engineering therapies continue to be developed in expectation of improving clinical outcomes. Results with appropriate follow-up are not yet available to indicate if such techniques are safe, cost-effective and reliable in the long-term.
“…Actually, are several manufacturers who research and develop the techniques of total intervertebral disc replacement in USA and Europe. The most important are: ProDisc® produce by Spine Solution Inc. [1], SB Charite® III develop by Link Spine Group Inc. [2] and Maverick® Total Disc, produce by DePuy Spine, Inc., Raynham, MA, USA. [3].…”
The purpose of this study was to analyze the behavior of a lumbar spine disc prosthesis with different materials. The study was performed at L4-L5 lumbar motion segment using the finite element method (FEM). A healthy Finite Element (FE) model was used as a reference with which to compare the results of the FE simulations of the artificial discs. The healthy and the artificial FE models were subjected to a combination of 0.5 MPa Compression pre-load and 10Nm of Flexion moment. The artificial FE models were based on Maverick artificial disc, and the three materials proposed for study the artificial disk were Titanium, Ceramic and CrCoMo alloy. The most suitable material for developed the artificial disc was the CoCrMo alloy due to: The von Mises stresses on the bone with which this artificial disc was in contact were reduced as much as possible and also, were very similar to the von Mises stresses obtained in the bones from the healthy disc.
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