In the Large helical device, a change of energetic particle mode is observed as He concentration is varied in ion-ITB type experiments, having constant electron density and input heating power but with a clear increase of central ion temperature in He rich discharges. This activity consists of bursty, but damped energetic interchange modes (EICs, X Du et al., Phys. Rev. Lett. 114 p.155003 (2015)), whose occurrence rate is dramatically lower in the He-rich discharges. Mechanisms are discussed for the changes in drive and damping of the modes with He concentration. These EIC bursts consist of marked changes in the radial electric field, which is derived from the phase velocity of turbulence measured with the 2D phase contrast imaging (PCI) system. Similar bursts are detected in edge fast ion diagnostics. Ion thermal transport by gyro-Bohm scaling is recognised as a contribution to the change in ion temperature, though fast ion losses by these EIC modes may also contribute to the ion temperature dependence on He concentration, most particularly controlling the height of an "edge-pedestal" in the Ti profile. The steady-state level of fast ions is shown to be larger in Helium rich discharges on the basis of a compact neutral particle analyser (CNPA), and the fast-ion component of the diamagnetic stored energy. These events also have an influence on turbulence and transport. The large velocity shear induced produced during these events transiently improves confinement and suppresses turbulence, and has a larger net effect when bursts are more frequent in Hydrogen discharges. This exactly offsets the increased gyro-Bohm related turbulence drive in Hydrogen which results in the same time-averaged turbulence level in Hydrogen as in Helium.