“…Endodontic regeneration can occur from various sources like the vital pulp cells in the root canal, the stem cells in the dental pulp , periodontal ligament from apical papilla (saad and Yousef saad, 1988;Gronthos et al, 2002;Cotti, Mereu and lusso, 2008). radiographic evaluation reveals the successfulness of endodontic treatment performed (Antony, Thomas and nivedhitha, 2020). We have numerous highly cited publications on well designed clinical trials and lab studies (Govindaraju, neelakantan and Gutmann, 2017;Azeem and sureshbabu, 2018;Jenarthanan and subbarao, 2018;Manohar and sharma, 2018;nandakumar and nasim, 2018;Teja, ramesh and Priya, 2018;Janani and sandhya, 2019;Khandelwal and Palanivelu, 2019;Malli sureshbabu et al, 2019;Poorni, srinivasan and nivedhitha, 2019;rajakeerthi and Ms, 2019;rajendran et al, 2019;ramarao and sathyanarayanan, 2019;siddique, nivedhitha and Jacob, 2019).…”