Two-Dimensional Nanomaterials for Photoinduced Antibacterial Applications

Abstract

Nanomaterials used as novel antimicrobial agents are developed to combat wide-spectrum bacteria as well as alleviate the problem of bacterial resistance to traditional antibiotics. Two-dimensional (2D) nanomaterials are regarded as promising and widely applicable wide-spectrum antibacterial nanoagents due to their outstanding characteristics, including large surface area, stable structure, good biocompatibility, and cheap raw materials, especially excellent photocatalytic or photothermal properties. The advantages of less resistance, rapid sterilization, local action mode, and non-invasive make 2D nanomaterials with photoinduced property stand out in novel sterilization agents. Here, we systematically summarize various kinds of 2D nanomaterials that were used in photoinduced antibacterial field and introduce the synthesis methods and physicochemical properties related to antibacterial capability. Besides, the sterilization mechanisms of different 2D nanomaterials are also introduced in detail including a direct temperature generation, ROS production or ROS-independent oxidative stress, or various synergistic antibacterial modes. Lastly, we have also discussed the current problems of 2D nanomaterials as light-inducing antibacterial agents and their future application prospects in the fields of biomedicine, sewage treatment, food, and other application scenarios. We envision that this review will assist investigators with quick and in-depth understanding of the latest progress in 2D nanomaterials for photoinduced sterilization, inspiring the development of multiply strategies to design and synthesize novel 2D materials with strong bactericidal capability and high biological safety, and expand 2D materials with photoinduced sterilization to more application scenarios.

Photoinduced Antibacterial Activity and Cytotoxicity of CdS Stabilized on Mesoporous Aluminosilicates and Silicates

“…where R is the reflectance (%). The optical band gap (Eg) for the synthesized photocatalysts was estimated using the Tauc model for direct allowed transitions by plotting (F(R) × hν) 2 versus hν followed by a linear extrapolation to intercept the energy axis.…”

“…All UV-Vis diffuse reflectance spectra had broad absorption region below 550 nm that is attributed to the charge transfer from the valence to the conduction band of CdS (Figure 5a). CdS band gap was determined by standard method by plotting (F(R) × hν) 2 for direct semiconductors versus hν, followed by linear extrapolation to intercept the energy axis [21]. Bang gap energy calculated using Tauc method equal to 2.36 eV for CdS/MCM-41 which is close to bulk CdS (2.4 eV), 2.45 eV for CdS/SBA-15, 2.47 eV for CdS/SBA-15-SH, 2.54 eV for CdS/MCM-41-HNTs and 2.58 eV for CdS/HNTs (Figure 5b).…”

“…Pharmaceutics 2022, 14, x FOR PEER REVIEW 9 of 14 was determined by standard method by plotting (F(R) × hν) 2 for direct semiconductors versus hν, followed by linear extrapolation to intercept the energy axis [21]. Bang gap energy calculated using Tauc method equal to 2.36 eV for CdS/MCM-41 which is close to bulk CdS (2.4 eV), 2.45 eV for CdS/SBA-15, 2.47 eV for CdS/SBA-15-SH, 2.54 eV for CdS/MCM-41-HNTs and 2.58 eV for CdS/HNTs (Figure 5b).…”

A Stable Quaternized Chitosan-Black Phosphorus Nanocomposite for Synergetic Disinfection of Antibiotic-Resistant Pathogens

“…The experiment was divided into six groups: (1) PBS, (2) PBS+NIR, (3) BP, (4) BP-QCS, (5) BP+NIR, and (6) BP-QCS +NIR. For groups (3) to (6), the concentration of BP or BP-QCS was 75 μg/mL. All groups were incubated for 1 h at 37 °C.…”

Recent Trends in Fascinating Applications of Nanotechnology in Allied Health Sciences

“…), and other alkalis (Rb, Li, etc.) metals, have been investigated for manufacturing the nanocomposites materials with 2D structures [6,7]. The hybrid nanomaterials are also employed for wider uses, such as optoelectronics, biomedicine, and catalytic actions.…”