Two-dimensional iron MOF nanosheet as a highly efficient nanozyme for glucose biosensing

Ai, Yan; Lu, Yuwan; Zhang, Xiaodan; Chen, Qiumeng; Huang, Yuming

doi:10.1039/d0tb01598a

Cited by 82 publications

(29 citation statements)

References 43 publications

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“…Nowadays, various nanozymes have been served as catalytic labels for multi-category signal amplification in newly developed immunoassays. Numerous studies revealed that metal NPs (Au, Ag, Pt, Pd) [85,86], metal oxide NPs (Fe 3 O 4 , CeO 2 , MnO 2 , CuO) [87][88][89][90][91][92], carbon-based (graphene oxide, carbon nitride, carbon dots) [93][94][95][96], and MOFs-based nanomaterials [97][98][99] with peroxidase-, catalase-, oxidase-, superoxide dismutase-mimicking properties.…”

Section: Nanozyme For Signal Amplificationmentioning

confidence: 99%

Advances in Visual Immunoassays for Sensitive Detection of Mycotoxins in Food—A Review

Liang

2021

The 1st International Electronic Conference on Chemical Sensors and Analytical Chemistry

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Mycotoxins are the toxic secondary metabolites naturally produced by fungi; their contamination in agricultural products and food severely threatens food safety and public health worldwide. The reliable, efficient, and sensitive quantification of mycotoxins in food has become increasingly challenging to tackle due to the complexity of food matrices and their low level. Visual detection has emerged as a popular trend toward miniaturization and simplification of mycotoxins assays yet is constrained with their limited sensitivity. This review mainly focuses on the various sensitive visual immunoassays for signal amplified detection of mycotoxins. These signal amplified immunoassays for the improved sensitivity of mycotoxins detection in food through nanomaterials for encapsulation enzyme, enzyme-mediated nanomaterials as the amplified signal readout, and nanozyme. Furthermore, the underlying principle and the advantages of visual immunoassays for mycotoxins have been proposed. And the challenges and perspectives have been proposed to develop improved efficient visual immunoassays for mycotoxins in food.

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Section: Nanozyme For Signal Amplificationmentioning

confidence: 99%

Advances in Visual Immunoassays for Sensitive Detection of Mycotoxins in Food—A Review

Liang

2021

The 1st International Electronic Conference on Chemical Sensors and Analytical Chemistry

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Section: Introductionmentioning

confidence: 99%

Two-dimensional metal-organic frameworks: from synthesis to bioapplications

Wang

Jin

et al. 2022

J Nanobiotechnol

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As a typical class of crystalline porous materials, metal–organic framework possesses unique features including versatile functionality, structural and compositional tunability. After being reduced to two-dimension, ultrathin metal-organic framework layers possess more external excellent properties favoring various technological applications. In this review article, the unique structural properties of the ultrathin metal-organic framework nanosheets benefiting from the planar topography were highlighted, involving light transmittance, and electrical conductivity. Moreover, the design strategy and versatile fabrication methodology were summarized covering discussions on their applicability and accessibility, especially for porphyritic metal-organic framework nanosheet. The current achievements in the bioapplications of two-dimensional metal-organic frameworks were presented comprising biocatalysis, biosensor, and theranostic, with an emphasis on reactive oxygen species-based nanomedicine for oncology treatment. Furthermore, current challenges confronting the utilization of two-dimensional metal-organic frameworks and future opportunities in emerging research frontiers were presented. Graphical Abstract

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“…[12] Addressing the limitations of natural enzymes such as low stability, high cost, and storage restrictions, nanozymes attracted a particular attention to enzymenanozymes biosensors elaboration. So, a plethora of peroxidase mimics, including metal-organic framework nanosheets, [13] nanoflowers, [14] nanodots, [15] and nanocages [16] etc., were coupled with oxidases for biosensing applications.…”

Section: Introductionmentioning

confidence: 99%

Nanozymes “Artificial Peroxidase”: Enzyme Oxidase Mixtures for Single‐Step Fabrication of Advanced Electrochemical Biosensors

et al. 2021

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We report the single-step fabrication of advanced electrochemical biosensors upon drop-casting of "artificial peroxidase", that is, oxidase-containing mixtures. Compared to bienzyme biosensors, we substitute peroxidase with more active and stable nanozymes based on catalytically synthesized Prussian Blue. The electroactivity of nanozymes in the sensing membrane was facilitated with carbon black nanoparticles, which resulted in record sensitivity of the H 2 O 2 transducer exceeding 1.1 A M À 1 • cm À 2. Both glucose and lactate oxidases were co-immobilized with nanozymes in alkoxysilane or perfluorosulfonated ionomer membranes. The proposed drop-casting approach results in biosensors that are advantageous over those conventionally produced upon layer-by-layer immobilization in terms of i) almost an order of magnitude increased sensitivity, ii) unsurpassed biosensor-to-transducer sensitivity ratio reaching the value of 0.3, and iii) three times extended operational lifetime.

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Two-dimensional iron MOF nanosheet as a highly efficient nanozyme for glucose biosensing

Abstract: Two-dimensional (2D) nanomaterials are attractive in catalysis due to their rich accessible active sites. Iron-based metal organic framework (MOF) is one of promising nanozymes because of its iron center and...

Cited by 82 publications

References 43 publications

Advances in Visual Immunoassays for Sensitive Detection of Mycotoxins in Food—A Review

Advances in Visual Immunoassays for Sensitive Detection of Mycotoxins in Food—A Review

Two-dimensional metal-organic frameworks: from synthesis to bioapplications

Nanozymes “Artificial Peroxidase”: Enzyme Oxidase Mixtures for Single‐Step Fabrication of Advanced Electrochemical Biosensors

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