Two-Dimensional Atrial Systolic Strain Imaging Predicts Atrial Fibrillation at 4-Year Follow-Up in Asymptomatic Rheumatic Mitral Stenosis

Ancona, R.; Pinto, S. Comenale; Caso, Pio; Salvo, Giovanni Di; Severino, Sergio; D’Andrea, Antonello; Calabrò, Raffaele

doi:10.1016/j.echo.2012.11.016

Cited by 76 publications

(79 citation statements)

References 41 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In 101 patients with rheumatic mitral stenosis, Ancona et al demonstrated reduced LA systolic strain, the degree of which correlated with worse cardiovascular outcomes during a 3-year follow-up, irrespective of LA volume, age and mitral valve area. LA systolic strain was also the most powerful predictor of new onset AF at 4-year follow-up (86).…”

Section: Valvular Heart Diseasementioning

confidence: 92%

Left atrial function: evaluation by strain analysis

Gan¹,

Ferkh²,

Boyd

et al. 2018

Cardiovasc. Diagn. Ther.

128

108

View full text Add to dashboard Cite

Abstract:The left atrium has an important role in modulating left ventricular filling and is an important biomarker of cardiovascular disease and adverse cardiovascular outcomes. While previously left atrial (LA) size was utilised, the role of LA function as a biomarker is increasingly being evaluated, both independently and also in combination with LA size. Strain analysis has been utilised for evaluation of LA function and can be measured throughout the cardiac cycle, thereby enabling the evaluation of LA reservoir, conduit and contractile function. Strain evaluates myocardial deformation while strain rate examines the rate of change in strain. This review will focus on the various types of strain analysis for evaluation of LA function, alterations in LA strain in physiological and pathologic states that alter LA function and finally evaluate its utility as a prognostic marker.

show abstract

Section: Valvular Heart Diseasementioning

confidence: 92%

Left atrial function: evaluation by strain analysis

Gan¹,

Ferkh²,

Boyd

et al. 2018

Cardiovasc. Diagn. Ther.

128

108

View full text Add to dashboard Cite

show abstract

“…Recently, alternative methods have been developed to measure myocardial deformation properties both by Doppler myocardial imaging-derived strain and by speckle tracking echocardiography strain, to detect early functional remodelling before anatomical alterations occur [2, 4–6, 31–34]. This LA remodelling process, for decreasing of its elastic properties, and LA enlargement, because of its thin-walled structure, have been regarded as important prognostic factors in various heart diseases.…”

Section: La Function and Left Atrial Myocardial Deformation Propermentioning

confidence: 99%

Left Atrium by Echocardiography in Clinical Practice: From Conventional Methods to New Echocardiographic Techniques

Ancona

Pinto

Caso

et al. 2014

The Scientific World Journal

Self Cite

View full text Add to dashboard Cite

Although often referred to as “the forgotten chamber”, compared with left ventricle (LV), especially in the past years, the left atrium (LA) plays a critical role in the clinical expression and prognosis of patients with heart and cerebrovascular disease, as demonstrated by several studies. Echocardiographers initially focused on early detection of atrial geometrical abnormalities through monodimensional atrial diameter quantification and then bidimensional (2D) areas and volume estimation. Now, together with conventional echocardiographic parameters, new echocardiographic techniques, such as strain Doppler, 2D speckle tracking and three-dimensional (3D) echocardiography, allow assessing early LA dysfunction and they all play a fundamental role to detect early functional remodelling before anatomical alterations occur. LA dysfunction and its important prognostic implications may be detected sooner by LA strain than by volumetric measurements.

show abstract

“…Among 580 patients without known atrial fibrillation or mitral valve disease, Hirose et al [18] found that left atrial speckle-tracking strain was the strongest overall predictor of incident atrial fibrillation; left atrial deformation 37% or less exhibited a positive predictive value (95% confidence interval) of 19% (16-22%) and a negative predictive value (95% confidence interval) of 99% (98-100%). In 101 patients with mild mitral stenosis in sinus rhythm and 70 healthy controls, Ancona et al [19] reported that speckle-tracking reservoir left atrial strain was the best predictor of incident atrial fibrillation, although the optimal discriminatory threshold in this patient population was 17.4%, which differs from the 37% threshold reported by Hirose et al [18].…”

Section: Key Pointsmentioning

confidence: 94%