Two depressed young patients with angina pectoris induced by microvascular dysfunction detected by stress perfusion cardiac magnetic resonance

Abstract

Background: Recent evidence indicates a link between depression and microvascular dysfunction, which may affect therapy options and prognosis. Case summary: We described two young depressed patients with angina. No obstructive coronary heart disease was detected by computed tomography coronary angiography or invasive coronary angiography. Determined by stress perfusion cardiac MRI, these two patients were diagnosed with microvascular angina. Discussion: The two cases emphasized that depression and microvascular angina can coexist inyoung patients. Negligence of mental disorder may cause insufficient treatments. Both psycho-regulatory interventions and heart disease medicine should be options for these patients. Keywords: Microvascular angina; Depression; Stress perfusion cardiac magnetic resonance; Case report.