Two decades of molecular surveillance in Senegal reveal rapid changes in known drug resistance mutations over time
Yaye D. Ndiaye,
Wesley Wong,
Julie Thwing
et al.
Abstract:Background
Drug resistance in Plasmodium falciparum is a major threat to malaria control efforts. Pathogen genomic surveillance could be invaluable for monitoring current and emerging parasite drug resistance.
Methods
Data from two decades (2000–2020) of continuous molecular surveillance of P. falciparum parasites from Senegal were retrospectively examined to assess historical changes in malaria drug resistance mutations. Several known drug resista… Show more
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