Two Cases of Vivax Malaria Accompanied by Splenic Complications (such as splenic rupture and splenic infarction)

Jung, Eun Jung; Choo, Eun Ju; Kim, Tae Hyong; Jeon, Min Hyok; Lee, Eun Jeung; Cho, Young Sin; Lee, Ho‐Young; Kim, Ji Yon

doi:10.3947/ic.2008.40.3.179

Cited by 1 publication

(1 citation statement)

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“…Domestic cases that were not found in PubMed were searched in KoreaMed (http:// koreamed.org/SearchBasic.php) using the keywords "spleen infarction, malaria," "splenic infarction, malaria," or "spleen rupture, malaria." [7][8][9] Reports were in Korean or English. Two investigators independently reviewed the articles and discordance was resolved by consensus.…”

Section: Methodsmentioning

confidence: 99%

Malaria-Induced Splenic Infarction

Hwang

Lee

2014

The American Society of Tropical Medicine and Hygiene

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Abstract. Splenic infarction is a rare complication of malaria. We report two recent cases of splenic infarction after Plasmodium vivax infection. No systematic review of malaria-induced splenic infarction was available, therefore we conducted a systematic review of the English, French, and Spanish literature in PubMed and KoreaMed for reports of malaria-associated splenic infarction from 1960 to 2012. Of the 40 cases collected on splenic infarction by Plasmodium species, 23 involved P. vivax, 11 Plasmodium falciparum, one Plasmodium ovale, and five a mixed infection of P. vivax and P. falciparum. Of the 40 cases, 2 (5.0%) involved splenectomy and 5 (12.5%) were accompanied by splenic rupture. The median time from symptom onset to diagnosis was 8.5 days (range, 3-90 days). Improved findings after treatment were observed in 8 (88.9%) of 9 patients with splenic infarction on follow-up by computed tomography or ultrasonography. All patients survived after treatment with the exception of one patient with cerebral malaria. Clinicians should consider the possibility of splenic infarction when malaria-infected patients have left upper quadrant pain.

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Section: Methodsmentioning

confidence: 99%