Two Cases of Hodgkin's Lymphoma after Allogeneic Hematopoietic Cell Transplantation

Jin, Sun; Kim, Kyung Ho; Kim, Gun Woo; Moon, Jie Hye; Kim, Gwang Il; Doyeun, Oh; Chong, So Young

doi:10.3904/kjm.2013.84.6.855

Korean J Med

2013

DOI: 10.3904/kjm.2013.84.6.855

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Two Cases of Hodgkin's Lymphoma after Allogeneic Hematopoietic Cell Transplantation

Sun Jin

Kyung Ho Kim²,

Gun Woo Kim³

et al.

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Cited by 2 publications

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“…HSCT, particularly in high-risk settings such as T-cell depletion, HLA-mismatched HSCT and EBV-seromismatched SOT. Jin et al[10] reported two cases of Hodgkin's lymphoma after allogeneic HSCT for acute myeloid leukemia.…”

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Fatal PTLD Accompanied by Rapid Lymphocyte Proliferation in the Early Phase of Allogeneic HSCT

Lee¹,

Kim²,

Lee³

et al. 2015

Korean J Med

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Post-transplant lymphoproliferative disorder (PTLD) is a spectrum of clinically and morphologically heterogeneous lymphoid proliferations of various clonal compositions that are observed after hematopoietic stem cell transplantation (HSCT) or solid organ transplantation. The majority of PTLD cases are associated with Epstein-Barr virus (EBV) infection, while overt peripheral blood (PB) or bone marrow (BM) involvement in PTLD is uncommon in early lesions. We report a 38-year-old woman with EBV-related PTLD, with BM and PB involvement, who presented with peripheral lymphocytosis as an early lesion 1 month after haploidentical HSCT for Philadelphia chromosome-positive acute lymphoblastic leukemia was performed during first complete remission. Although PB or BM involvement of PTLD after HSCT is uncommon in early lesions, peripheral lymphocytosis can be an initial presenting manifestation of PTLD, as in this case.

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confidence: 99%

Fatal PTLD Accompanied by Rapid Lymphocyte Proliferation in the Early Phase of Allogeneic HSCT

Lee¹,

Kim²,

Lee³

et al. 2015

Korean J Med

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Hodgkin's Lymphoma after Autologous Hematopoietic Stem Cell Transplantation for Angioimmunoblastic T-cell Lymphoma

Park

jiwan

et al. 2014

Korean J Med

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Post-transplantation lymphoproliferative disorder (PTLD) is a serious complication that can develop after either solid organ or hematopoietic stem cell transplantation (HSCT). The incidence of Hodgkin's lymphoma (HL) ranges from 0.5-1.0% of PTLD after HSCT without T-cell depletion. Here, we report a case of HL-PTLD that occurred after autologous peripheral blood stem cell transplantation for an angioimmunoblastic T-cell lymphoma (AITL). A 36-year-old patient developed fever and chills with multiple lymphadenopathies at day 673 after auto-HSCT for AITL. Three months after the transplant, the patient developed fever with elevated plasma Epstein-Barr virus (EBV)-PCR values. The excisional biopsy revealed HL at Ann Arbor stage IIIB. A total of 8 cycles of chemotherapy with ABVD please define were performed, and the patient has remained disease-free. To our knowledge, this is first case report of HL-PTLD after auto-PBSCT in Korea.

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Two Cases of Hodgkin's Lymphoma after Allogeneic Hematopoietic Cell Transplantation

Cited by 2 publications

References 8 publications

Fatal PTLD Accompanied by Rapid Lymphocyte Proliferation in the Early Phase of Allogeneic HSCT

Fatal PTLD Accompanied by Rapid Lymphocyte Proliferation in the Early Phase of Allogeneic HSCT

Hodgkin's Lymphoma after Autologous Hematopoietic Stem Cell Transplantation for Angioimmunoblastic T-cell Lymphoma

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