Two case reports of synchronous unilateral pleomorphic adenoma and cystadenolymphoma of the parotid gland with literature review

Heine, Daniela; Zenk, Johannes; Psychogios, Georgios

doi:10.15557/jou.2018.0055

Cited by 9 publications

(7 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Warthin's tumours were the most common benign lesions found in 201 (42.4%) parotid glands followed by pleomorphic adenomas in 138 (29.1%) of these cases. In two patients, both WT and PA were evident simultaneously in their histological examinations and were excluded from further comparisons [5]. Moreover, 12 patients had bilateral WT, whereas no patients with bilateral PA were identified.…”

Section: Resultsmentioning

confidence: 99%

Warthin’s tumour seems to be the most common benign neoplasm of the parotid gland in Germany

Psychogios

Vlastos

Thölken

et al. 2020

Eur Arch Otorhinolaryngol

Self Cite

View full text Add to dashboard Cite

Purpose Recent reports indicate an increase in the prevalence of Warthin's tumours (adenolymphoma) with percentages which exceed that of pleomorphic adenomas (PA) in the same registries. The purpose of this study is to analyse a large cohort of benign parotid tumours in relation to various demographic and other patients' characteristics that might affect their incidence. Methods A retrospective review of prospective collected data was performed on all patients who have been operated for a parotid mass in the last 5 years. A total of 474 patients with benign lesion were included in the study. Age, gender, smoking status, histological diagnosis, site of lesion, and size of tumour were recorded. Results Warthin's tumours were the most common benign lesions, found in 201 (42.4%) parotic glands followed by pleomorphic adenomas found in 138 (29.1%) of these surgical cases. Patients with WT had a mean age of 61.6 years instead of 52 years for PA patients (t = 6.589, p < 0.001). The vast majority (93%) of patients with WT had a current or previous history of smoking compared with 47% of PA patients (p = 0.001). There was a male predominance regarding WT with a male:female (M:F) ratio of 2.3:1, whereas the corresponding ratio of PA was 1:1.4. Conclusions This study confirms the increased regional prevalence of WT reported in studies mainly carried out in central Europe. This could affect future management of WT, which remains largely controversial due to the extremely low malignant potential reported, concurrently with its higher rates of multiplicity and recurrence, as well as the moderately accurate results of FNA biopsies.

show abstract

Section: Resultsmentioning

confidence: 99%

Warthin’s tumour seems to be the most common benign neoplasm of the parotid gland in Germany

Psychogios

Vlastos

Thölken

et al. 2020

Eur Arch Otorhinolaryngol

Self Cite

View full text Add to dashboard Cite

show abstract

“…Warthin's tumors tend to occur multifocally and if this is the case, usually a subtotal or total parotidectomy is necessary [75]. The most common combination of multiple synchronous parotid tumors are multiple Warthin's tumors, but other combinations are also possible and need to be assessed carefully [76]. Furthermore, Warthin's tumors tend to cause local inflammation that complicate surgery and might necessitate a more extended surgical technique [77,78].…”

Section: Other Factors Influencing Decision Makingmentioning

confidence: 99%

Review of surgical techniques and guide for decision making in the treatment of benign parotid tumors

Psychogios

Bohr

Constantinidis

et al. 2020

Eur Arch Otorhinolaryngol

Self Cite

View full text Add to dashboard Cite

Purpose Surgical treatment of benign parotid tumors has developed in the direction of less invasive procedures in recent years and has raised great debate about the best surgical approach. Aim of this article is to analyse anatomical and other factors that are important in selection of the appropriate surgical technique in treatment of benign parotid tumors. Furthermore, to discuss the risk of complications and recurrent disease according to selected operation. Finally, to define patient selection criteria to facilitate decision making in parotid surgery and become a guide for younger surgeons. Methods Literature review and authors' personal opinions based on their surgical experience. Results All possible surgical techniques for benign parotid surgery with advantages and disadvantages are being described. An algorithm with anatomical and other criteria influencing decision making in benign parotid surgery is presented. Conclusion Surgeons nowadays have many options to choose from for benign parotid surgery. ECD is one of the many surgical techniques available in parotid surgery and can achieve excellent results with proper training and if used for proper indications. PSP is mainly indicated in large tumors of the caudal part of the PG (ESGS level II). SP represents a universal solution in parotid surgery and should be the first technique young surgeons learn. TP has only few but important indications in benign parotid surgery. Surgeons need to carefully consider the patient and his/her preoperative imaging as well as her or his own special expertise to select the most appropriate surgical technique.

show abstract

“…Instead of using FNAC, they employed elastography (Virtual Touch Imaging Quantification, VTIQ) as an additional diagnostic tool. In this way, the physical stiffness, which can be used as a potential marker for malignancy, was successfully assessed and interpreted prior to surgery [ 22 ].…”

Section: Discussionmentioning

confidence: 99%

“…In the course of multiple parotid tumors, a possible combination of a benign neoplasm with a malignant lesion, in most of the cases a Warthin tumor and mucoepidermoid carcinoma, should be considered [ 22 , 23 ]. Ochal-Choinska et al provided a comprehensive literature overview of known cases of simultaneous, unilateral parotid gland tumors of benign and malignant histology [ 24 ].…”

Section: Discussionmentioning

confidence: 99%

Uncommon Coexistence of Pleomorphic Adenoma and Warthin’s Tumor in a Painfully Swollen Left Parotid Gland: A Surgical Case Report

Klamminger,

Issing,

Burck

et al. 2023

Am J Case Rep

View full text Add to dashboard Cite

Patient: Female, 54-year-old Final Diagnosis: Synchronous benign pleomorphic adenoma and Warthin’s tumor Symptoms: Progressive and painful swelling of the left parotid gland for the last six months with a marked increase in size in recent weeks Clinical Procedure: Surgery Specialty: Pathology Objective: Rare coexistence of disease or pathology Background: Benign pleomorphic adenoma is the most common primary tumor of the salivary glands and mainly arises in the parotid gland. Warthin’s tumor, or papillary cystadenoma lymphomatosum, represents <30% of benign parotid tumors. The simultaneous occurrence of multiple parotid tumors is rarely described – depending on the corresponding histology (different/identical), the time of their occurrence (synchronous/metachronous), as well as their location (unilateral/bilateral), multiple parotid tumors can be further sub-classified. Case Report: We describe the case of a 54-year-old female patient with progressive and painful swelling of the left parotid gland for the last 6 months. During extra-oral examination, a bulging, displaceable mass of approximately 3 cm was determined. A subsequent MRI (magnetic resonance imaging) examination revealed a multifocal lesion but failed to provide a decisive clue as to the tumor entity of the lesion, and a lateral (superficial) parotidectomy was performed. Postoperative histomorphological interpretation allowed the final pathological diagnosis of synchronous, unilateral occurrence of a pleomorphic adenoma as well as a Warthin’s tumor. Conclusions: This report presents a rare case of synchronous unilateral parotid tumors and supports that benign pleomorphic adenoma and Warthin’s tumor are the most common associations. Since clinical examination, MRI imaging, and even cytological assessment could be misleading in the detection of synchronous ipsilateral multiple parotid gland tumors, our report also highlights the importance of timely and accurate diagnosis with histo-pathology to plan surgery and to exclude malignant transformation, which is a rare but important association with both types of primary salivary gland tumor.

show abstract

Two case reports of synchronous unilateral pleomorphic adenoma and cystadenolymphoma of the parotid gland with literature review

Cited by 9 publications

References 10 publications

Warthin’s tumour seems to be the most common benign neoplasm of the parotid gland in Germany

Warthin’s tumour seems to be the most common benign neoplasm of the parotid gland in Germany

Review of surgical techniques and guide for decision making in the treatment of benign parotid tumors

Uncommon Coexistence of Pleomorphic Adenoma and Warthin’s Tumor in a Painfully Swollen Left Parotid Gland: A Surgical Case Report

Contact Info

Product

Resources

About