We investigate the properties of Bose-Einstein condensates (BECs) in a two-dimensional quasiperiodic optical lattice (OL) with eightfold rotational symmetry by numerically solving the Gross-Pitaevskii equation. In a stationary external harmonic trapping potential, we first analyze the evolution of matter-wave interference pattern from periodic to quasi-periodic as the OL is changed continuously from four-fold periodic and eight-fold quasi-periodic. We also investigate the transport properties during this evolution for different interatomic interaction and lattice depth, and find that the BEC crosses over from ballistic diffusion to localization. Finally, we focus on the case of eightfold symmetric lattice and consider a global rotation imposed by the external trapping potential. The BEC shows vortex pattern with eightfold symmetry for slow rotation, becomes unstable for intermediate rotation, and exhibits annular solitons with approximate axial symmetry for fast rotation. These results can be readily demonstrated in experiments using the same configuration as in Phys. Rev. Lett. 122, 110404 (2019).