Two autopsy cases of pulmonary leukemic infiltration mimicking severe pneumonia in patients with acute myeloid leukemia

Iizuka, Hiroko; Mori, Yosuke; Fukuda, Yasutaka; Iwao, Noriaki; Koike, Michiaki; Noguchi, Masaaki

doi:10.1016/j.lrr.2021.100269

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2022

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“…As a result, many patients with AML die from severe infection and hemorrhage. Multiple organ failure, a clinical syndrome due to the failure of several organs that is fatal without intervention [ 2 ], is also a possible cause of death in AML patients [ 3 ], but there have been surprisingly few detailed histopathologic reports on such cases [ 4 ]. Herein, we describe multiple organ dysfunction syndrome due to multiple organ infarctions based on an autopsy case we experienced.…”

Section: Introductionmentioning

confidence: 99%

Drastic Multiorgan Dysfunction Due to Severe Leukostasis: A Case Report

Tada¹,

Kikuchi²,

Murase³

et al. 2022

Cureus

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Leukostasis is a life-threatening complication that causes vascular occlusion leading to organ damage in leukemia patients. Organs with impairment due to leukostasis are usually the lungs and kidneys, but other organs may also be damaged. We experienced an autopsy case of severe infarction in multiple organs including the spleen probably due to leukostasis in a patient with acute myeloid leukemia.

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Section: Introductionmentioning

confidence: 99%