Two antifungal active triterpenoid saponins from the seeds ofLathyrusplants

Abstract

Two novel triterpenoid glycosides have been isolated from butanolic seeds extract of two varieties of Lathyrus plants, i.e. Lathyrus ratan and Lathyrus aphaca. Their structures were elucidated as 3-O-[β-D-glucuronopyranosyl-(1 → 4)-α-L-arabinopyranosyl-(1 → 2)-α-L-arabinopyranosyl]-olean-11,13(18)-dien-28-oic acid (1) and 3-O-{β-D-xylopyranosyl-(1 → 2)-β-D-glcopyranosyl-(1 → 4)-[β-D-glucopyranosyl-(1 → 2)]-β-D-xylopyranosyl}-2,16α-dihydroxy-4-hydroxymethyl urs-12-en-28-oic acid (2) on the basis of spectral evidences, i.e. FTIR, (1)H-NMR, (13)C-NMR, ESI-MS and FAB-MS data. The isolated saponins were tested for their antifungal activity. Compound 1 showed maximum inhibition against Colletotrichum dematium (77.8%), whereas compound 2 showed maximum inhibition against Alternaria alternata (53.9%).

Antifungal and Antibacterial Activity of <em>Lathyrus Aphaca L.</em> Mediated Green Synthesized CdS Nanoparticles and their Characterization

“…The Bacillus subtilis, Staphylococcus aureus, Streptococcus, Escherichia coli, and Klebsiella pneumoniae which has 13.02, 28.82, 31.06, 26.89, and 10.2mm of inhibition zone respectively by 1000µg/mL of CdS-LA hybrid nanoparticles as compared to the inhibition shown by standard Gentamicin sulphate (40µg/mL) (Table 1). The activity was shown by CdS-LA hybrid nanoparticles is due to the phytochemicals of the plant extract that are present on the surface of CdS nanoparticles as a reducing and capping agent, which is also responsible for the antifungal activity of the CdS-LA hybrid nanoparticles which was confirmed by the previous study on the antifungal activity of Lathyrus plant seeds [21].…”

Antimicrobial and Anti-Inflammatory Activity of Some <i>Lathyrus</i> L. (Fabaceae) Species Growing in Turkey

“…of research on the antibacterial screening of Lathyrus species. According to the literature, from butanolic extracts of L. aphaca seeds two triterpenoid saponins were isolated that showed antifungal activity against Colletotrichum dematium and Alternaria alternata 21. Inhibition of growth of Xanthomonas campestris pv.…”

Διερεύνηση Της Επίδρασης Φυσικών Προϊόντων, Προερχόμενων Από Φυτά Της Ελληνικής Χλωρίδας Στο Μεταβολισμό Των Οστών

“…Και στα δύο γένη απαντώνται φλαβονοειδή (καιμφερόλη, κερκετίνη, λουτεολίνη κ.ά.) ως γενίνες ή με τη μορφή γλυκοζυλιωμένων παραγώγων, αλλά και προανθοκυανιδίνες και σαπωνίνες [284,285,286,287,288]. Σε όλους τους προαναφερόμενους μεταβολίτες έχουν αποδοθεί σημαντικές δράσεις, ενώ σε μελέτη των Lee et al, (2011) [289] φάνηκε ότι η κατανάλωση διαφόρων ειδών που ανήκουν στην ευρύτερη κατηγορία των οσπρίων δρα ευεργετικά στα οστά ωοθηκεκτομηθέντων επίμυων.…”