Twin Study of Central Auditory Processing Disorder

Abstract

We compared auditory, cognitive, and language test results in a pair of dizygotic twins, one of whom showed symptoms of central auditory processing disorder (CAPD). Results highlight the importance of testing binaural function. In particular, electrophysiologic measures of dichotic listening effectively demonstrated the auditory-specific nature of this child's listening problems. The importance of a thorough and comprehensive evaluation of children suspected of CAPD is stressed. Abbreviations: ABR = auditory brainstem response, CAPD = central auditory processing disorder, CELF = Clinical Evaluation of Language Functions, ERP = event-related potential, PPST = Pitch Pattern Sequence Test, PST = Phonemic Synthesis Test, RASP = Rapidly Alternating Speech Perception, SCAN = Screening Test for Auditory Processing, SSW = Staggered Spondaic Word Test, TTC = Token Test for Children, WISC-III = Wechsler Intelligence Scale for Children-III

Potencial evocado cognitivo e desordem de processamento auditivo em crianças com distúrbios de leitura e escrita

“…This study and others done on children with learning disorders used speech-in-noise and SSW tests to reveal the presence of auditory disorders and compromised hearing skills 27 , the latter also reflected on P300 28 , 29 .…”

Dissociation of sensitivity and response bias in children with attention deficit/hyperactivity disorder during central auditory masking.

“…Current results are consistent with previous findings indicating no deficit in central auditory function for nonspeech stimuli (Pillsbury et al, 1995). Although children with ADHD exhibit decreased performance on tests measuring central auditory function (Chermak et al, 1999; Gascon et al, 1986; Riccio et al, 1994), many of the tasks used to assess central auditory function use speech and degraded speech stimuli (Ferre & Wilber, 1986; Gascon et al, 1986; Jerger et al, 1991). Because ADHD exhibits substantial comorbidity with RD (Shaywitz & Shaywitz, 1994) and because children with RD may exhibit deficits in processing speech stimuli (Brady, Shankweiler, & Mann, 1983; Cornelissen, Hansen, Bradley, & Stein, 1996; de Gelder & Vroomen, 1998; de Weirdt, 1988; Freeman & Beasley, 1978; Godfrey et al, 1981), the potential presence of children with RD in experimental groups may have affected results in some studies.…”

Cutting Through the Noise: Noise-Induced Cochlear Synaptopathy and Individual Differences in Speech Understanding Among Listeners With Normal Audiograms

“…Yet, interest in noise-induced CS persists because evidence in animal models suggests that it may contribute to a particularly distressing auditory perceptual deficit: impaired speech-in-noise perception in adults with NHTs. This symptomology, which has been labeled auditory processing disorder (e.g., Palfery & Duff 2007), King-Kopetzky syndrome (Hinchcliffe 1992), or obscure auditory dysfunction (Saunders & Haggard 1989) has been linked to a broad range of deficits, from peripheral (Shaw et al 1996; Zhao & Stephens 2000; Zhao & Stephens 2006; Badri et al 2011) to central (Jerger et al 1991; Saunders & Haggard 1992; Zhao & Stephens 2000). CS may be an additional candidate to explain this constellation of symptoms; synaptic loss reduces the number of available AN fibers (particularly fibers with relatively greater importance for encoding loud sound; Furman et al 2013) and is thus thought to impair perception of speech in the presence of competing auditory signals much more than it affects speech perception in quiet (e.g., Lopez-Poveda 2014).…”