Twin cantilevers with a nanogap for single molecule experimentation

Lazzarino, Marco; Marchi, Elena De; Bressanutti, Massimo; Vaccari, Lisa; Cabrini, Stefano; Schmid, Chiara; Poetes, Rosa; Scoles, G.

doi:10.1016/j.mee.2006.01.263

“…where C 1 , C 2 , C 3 can be determined from (16). Putting the expressions of C z from ( 16) and ( 17) in (15) C ox for different patterns can be obtained.…”

Section: Concave and Convex Patternsmentioning

confidence: 99%

Analytical Modeling of Sensitivity Parameters Influenced by Practically Feasible Arrangement of Bio-molecules in Dielectric Modulated FET Biosensor

Das

¹

,

Chattopadhyay²,

Chanda³

et al. 2021

Preprint

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In this paper, analytical modeling of a Dielectric Modulated Double Gate Field Effect Transistor (DM-DGFET) for biosensing application is presented with extensive data analysis. Firstly, the size of the nanogaps and arrangements of biomolecules in those gaps are optimized with respect to the sensitivity of the above sensor. The optimized DM-DGFET is next analyzed on the basis of its modeling and simulation. This paper addresses novel issues arising from arrangements of biomolecules, especially from practical point of view. Effect of probe placement due to steric hindrance and random nature of biomolecules, are also considered. The capacitances associated with the nanogaps occupied by biomolecules, following various arrangements, are modeled. Expressions of the threshold voltage, drain current and its sensitivity in terms of variations are also derived using the capacitance model. A comparative study of the proposed and the existing architectures is made. The influence of process variation on the sensitivity of the sensor is also studied. The results from the proposed analytical model are validated with the simulated data obtained from TCAD device simulator. In conclusion, the proposed DM-DGFET based biosensor architecture will emerge as an optimal model, very useful for the study on this field in future.

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“…Hence, accurate methods to test and evaluate the mechanical properties is a very important aspect. Several methods are proposed for finding the mechanical properties e.g., Young's modulus, Poisson's ratio [5,[14][15][16][17]. Static analyses of 2-2 multi-layered piezoelecttric curved composites is discussed in [18,19] v. Subrahmanyam [14] proposed a method of evaluating the Young's modulus of different micro-machined structures such as polysilicon and fJ-SiC cantilever beams.…”

Section: Materials and Manufacturing Aspecfsmentioning

confidence: 99%

“…Literature seems to suggest that the elastic behavior and thus elastic constants of thin films can differ significantly from their bulk counterparts (see for example [16] and references therein). The reason attributed was that the specific microstructure such as texture, defects, interface mixing and size effects come into play.…”

Section: Materials and Manufacturing Aspecfsmentioning

confidence: 99%

“…A system of 20 periods of Figure 4. The radius of curvature of the bent beam, alternating layers of 6 nm thick W-Iayer and 18 nm R, is reported [3] to be thick eu-Iayer on Kapton® was studied in [16] to illustrate the framework to study elastic properties of polycrystalline thin films. The experiments revealed that the X-ray strain was maximum at outermost layers, thus corroborating the observation regarding the neutral axis mentioned in [8].…”

Section: Materials and Manufacturing Aspecfsmentioning

confidence: 99%

See 1 more Smart Citation

Nano/Micro-Electro-Mechanical Systems for Sensor Applications: A Brief Review

Subrahmanyam

¹

,

Rao

²

,

Ramamurthy

³

et al. 2010

IETE Journal of Education

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“…In this type of biosensor devices, formation of a nanogap involves a thin film deposition and subsequent wet etching processes. This reduces the complications in lithographic process associated with the planar nanogap FETs [13][14][15][16][17]. As sensitivity is the prime concern of biosensors, search for highly sensitive biosensor is still in progress.…”

Section: Introductionmentioning

confidence: 99%

Analytical Modeling of Sensitivity Parameters Influenced by Practically Feasible Arrangement of Bio-Molecules in Dielectric Modulated FET Biosensor

Das

¹

,

Chattopadhyay²,

Chanda³

et al. 2022

Silicon

View full text Add to dashboard Cite

In this paper, analytical modeling of a Dielectric Modulated Double Gate Field Effect Transistor (DM-DGFET) for biosensing application is presented with extensive data analysis. Firstly, the size of the nanogaps and arrangements of biomolecules in those gaps are optimized with respect to the sensitivity of the above sensor. The optimized DM-DGFET is next analyzed on the basis of its modeling and simulation. This paper addresses novel issues arising from arrangements of biomolecules, especially from practical point of view. Effect of probe placement due to steric hindrance and random nature of biomolecules, are also considered. The capacitances associated with the nanogaps occupied by biomolecules, following various arrangements, are modeled. Expressions of the threshold voltage, drain current and its sensitivity in terms of variations are also derived using the capacitance model. A comparative study of the proposed and the existing architectures is made. The influence of process variation on the sensitivity of the sensor is also studied. The results from the proposed analytical model are validated with the simulated data obtained from TCAD device simulator. In conclusion, the proposed DM-DGFET based biosensor architecture will emerge as an optimal model, very useful for the study on this field in future.

show abstract

Twin cantilevers with a nanogap for single molecule experimentation

Cited by 9 publications

References 8 publications

Analytical Modeling of Sensitivity Parameters Influenced by Practically Feasible Arrangement of Bio-molecules in Dielectric Modulated FET Biosensor

Analytical Modeling of Sensitivity Parameters Influenced by Practically Feasible Arrangement of Bio-molecules in Dielectric Modulated FET Biosensor

Nano/Micro-Electro-Mechanical Systems for Sensor Applications: A Brief Review

Analytical Modeling of Sensitivity Parameters Influenced by Practically Feasible Arrangement of Bio-Molecules in Dielectric Modulated FET Biosensor

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