Twenty-year perspective of randomized controlled trials for surgery of chronic nonspecific low back pain: citation bias and tangential knowledge

Andrade, Nicholas S.; Flynn, John P.; Bartanusz, Viktor

doi:10.1016/j.spinee.2013.06.071

Cited by 30 publications

(28 citation statements)

References 81 publications

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“…Jannot et al (5) retrieved citation counts of specific therapeutic intervention studies and found that studies with statistically significant findings were cited twice as often as those with nonsignificant findings. Similarly, Andrade et al (15) reported that trials that reported favorable outcomes for surgery to alleviate chronic nonspecific low back pain tended to be cited more often than those that reported less favorable results.…”

Section: Discussionmentioning

confidence: 99%

Don't Let the Truth Get in the Way of a Good Story: An Illustration of Citation Bias in Epidemiologic Research

Kivimäki

Batty

Kawachi

et al. 2014

American Journal of Epidemiology

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Section: Discussionmentioning

confidence: 99%

Don't Let the Truth Get in the Way of a Good Story: An Illustration of Citation Bias in Epidemiologic Research

Kivimäki

Batty

Kawachi

et al. 2014

American Journal of Epidemiology

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“…Chronic lower back pain (CLBP) is prevalent worldwide in all age groups, and is associated with significant morbidity and high health care costs 12. CLBP treatments are multimodal, including medication, injection, physical therapy, exercise, back school, and sometimes surgery 3.…”

Section: Introductionmentioning

confidence: 99%

Efficacy and Safety of Different Aceclofenac Treatments for Chronic Lower Back Pain: Prospective, Randomized, Single Center, Open-Label Clinical Trials

et al. 2017

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PurposeNonsteroidal anti-inflammatory drugs are a mainstay for medical treatment of chronic lower back pain (CLBP). Increased dose intervals for medication have been associated with increased patient adherence to prescriptions. The purpose of this clinical trial was to compare the efficacy and safety of a once daily dose of aceclofenac controlled release (CR) and a twice daily dose of aceclofenac for CLBP management.Materials and MethodsA prospective, randomized, single center, open-label clinical trial was performed to compare the efficacy and safety of aceclofenac CR (200 mg once daily) to aceclofenac dose (100 mg twice daily). Fifty patients in each group were enrolled for the study. The primary end point was Visual Analogue Scale (VAS) change at baseline to that at 2 weeks after medication and safety profiles. Also, change in quality of life measured by EuroQoL 5D (EQ-5D) and Oswestry Disability Index (ODI) functional score for the lumbar spine were also assessed.ResultsWithin groups at pre- and post-treatment, there were significant VAS reductions for aceclofenac CR and aceclofenac (p=0.028). EQ-5D increased significantly in both groups (p=0.037). ODI scores decreased significantly in both groups (p=0.012). However, there were no significant differences between aceclofenac CR and aceclofenac at pre- and post-treatment. Patients with aceclofenac CR showed significant increases in heartburn and indigestion and adverse gastrointestinal effects, compared to aceclofenac.ConclusionIn patients with CLBP, aceclofenac CR and aceclofenac demonstrated significant symptomatic pain relief, improvement in quality of life and functional scores. Aceclofenac CR slightly increased gastrointestinal adverse effects, such as heartburn and indigestion.

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“…679 Nevertheless, there is ample evidence to assert that LTDR is noninferior (and possibly superior) to lumbar fusion in patients with recalcitrant symptoms of back and/or radicular pain attributable to LDDD. The challenge rests on making this procedure more accessible to patients, to surgeons, and to health care facilities, and therefore addressing the logistic, financial, and regulatory issues that hamper the safe introduction of LTDR to a facility.…”

mentioning

confidence: 99%

We Need to Talk about Lumbar Total Disc Replacement

Beatty

2018

Int J Spine Surg

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Twenty-year perspective of randomized controlled trials for surgery of chronic nonspecific low back pain: citation bias and tangential knowledge

Cited by 30 publications

References 81 publications

Don't Let the Truth Get in the Way of a Good Story: An Illustration of Citation Bias in Epidemiologic Research

Don't Let the Truth Get in the Way of a Good Story: An Illustration of Citation Bias in Epidemiologic Research

Efficacy and Safety of Different Aceclofenac Treatments for Chronic Lower Back Pain: Prospective, Randomized, Single Center, Open-Label Clinical Trials

We Need to Talk about Lumbar Total Disc Replacement

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