Twenty-Two Year Experience with the Omniscience Prosthetic Heart Valve

Abstract

This study was designed to evaluate the long-term clinical results of the Omniscience tilting disc valve. Omniscience valves were implanted in 51 patients (mean age, 50 +/- 10 years); 18 had aortic valve, 24 had mitral valve, and 9 had both aortic and mitral valve replacements. Oral warfarin potassium and dipyridamole were prescribed as our anticoagulant therapy. Preoperatively, 42 patients were in New York Heart Association class III or IV, and 23 of 25 surviving patients were in class I or II after operation. There were 2 (3.9%) early deaths and 23 late deaths (3.5 +/- 0.7% per patient-year). Cardiac related mortality including congestive heart failure, sudden death, and thromboembolism, and hemorrhagic complications were seen in 16 patients. Overall survival at 10, 15, and 20 years was 77 +/- 6%, 62 +/- 7%, and 46 +/- 7%, respectively. Thromboembolic complications were seen in 5 patients, for a rate of 0.8 +/- 0.3% per patient-year; similarly, hemorrhagic complications were also seen in 5 patients. Nonstructural prosthetic valve dysfunction was seen in 4 patients, for a rate of 0.6 +/- 0.3% per patient-year, and sudden death was seen in 2, a rate of 0.3 +/- 0.2% per patient-year. The Omniscience prosthesis demonstrated excellent postoperative clinical status with low rates of valve related complications.

Structural valve deterioration of a mitral Carpentier-Edwards pericardial bioprosthesis in an 87-year-old woman 16 years after its implantation

“…The differential calcification of the leaflets of the same CEP valve is thought to be related to the different bovine origin of the component tissues of the valve. The imbalance of calcification in the three leaflets can cause imbalance of the tension between these leaflets, increasing the risk of leaflet tear [6,7]. In our patient, the tear was noted in the leaflet that showed no calcification, while the other two leaflets showed calcification.…”

3D transesophageal echocardiography and radiography of mitral valve prostheses and repairs

“…During valve closure, small gaps at the perimeter of the valve create minimal regurgitation which reduces transvalvular energy loss . The Omniscience mechanical valve is depicted in Figure and Movie ,.…”

“…8 During valve closure, small gaps at the perimeter of the valve create minimal regurgitation which reduces transvalvular energy loss. 22,23 The…”