Twenty-nail dystrophy of childhood

Abstract

Twenty-nail dystrophy is an idiopathic nail dystrophy that begins insidiously in early childhood. All 20 nails are uniformly affected with excessive longitudinal striations and loss of nail luster. The skin and its ectodermal derivatives are otherwise normal. Twenty-nail dystrophy is believed to be a self-limited abnormality that resolves slowly with age.

Unilateral trachyonychia in a patient with reflex sympathetic dystrophy

“…16 Trachyonychia has also been observed in alopecia areata, 17 atopic dermatitis, 18 and Down syndrome. 19 Tosti et al 16 have describe the pathogenesis of trachyonychia. The nail changes in trachyonychia occur primarily due to damage to the nail matrix.…”

Follow up of 12 patients with trachyonychia

“…3,4 Since these original reports, most authors have used these terms in both children and adults. Our study confirms that trachyonychia may affect patients from all age groups.…”

Lichen Planus Limited to the Nails in Childhood: Case Report and Literature Review

“…Especially in children, nail lichen pianus can occasionally have two peculiar clinical features that have been referred to as 20-nail dystrophy and idiopathic atrophy of the nails. The term 20-nail dystrophy was first used by Hazelrigg et al (6) to describe six children affected by an idiopathic nail dystrophy that began insidiously in early childhood and was characterized by excessive longitudinal striations and loss of nail luster. Twenty-nail dystrophy does not occur only in children, histopathologic data indicate it can be a clinical symptom of various diseases, including alopecia areata, lichen pianus, and psoriasis (7)(8)(9).…”