Twelve-Month Incidence of Depressive Symptoms in Suburb-Dwelling Chinese Older Adults: Role of Sarcopenia

Chen, Xiaoyu; Guo, Jing; Han, Peipei; Fu, Liyuan; Jia, Liye; Yu, Hairui; Yu, Xinguang; Hou, Lin; Wang, Lu; Zhang, Wen; Niu, Kaijun; Guo, Qi

doi:10.1016/j.jamda.2018.07.017

Cited by 35 publications

(45 citation statements)

References 44 publications

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“…Our results are in agreement with previous studies [11,[22][23][24],which reported that sarcopenia was associated with a higher risk of depressive symptoms in the elderly. However, con icting results have also been reported.…”

Section: Discussionsupporting

confidence: 94%

“…Sarcopenia, de ned as age-related loss of muscle mass and function [9], is a morbid condition in older adults that can result in serious health consequences, such as falls, disability and mortality [10]. Although the causal association between sarcopenia and depressive symptoms is still unclear, our previous cohort study showed that sarcopenia was an independent risk factor of depressive symptoms in suburb-dwelling older adults [11]. Furthermore, previous studies revealed that there may be an interactive relationship between sarcopenia and CHD [12][13][14].…”

Section: Introductionmentioning

confidence: 99%

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Sarcopenia and Coronary Heart Disease Synergistically Increase the Risk of New Onset Depressive Symptoms in Older Adults

Chen¹,

Han²,

Yu³

et al. 2020

Preprint

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Background: It is well known that psychological and physical are very common among the elderly. This study aimed to investigate the additive effects of coronary heart disease (CHD) and sarcopenia on the risk of new onset depressive symptoms in older adults. Methods: The prospective cohort study comprised 897 Chinese community-dwelling participants who were aged 60 years and older (386 men; mean age 66.9±5.9 years) without depressive symptoms at baseline, recruited from Chadian of Tianjin, China. Sarcopenia was defined according to the Asian Working Group for Sarcopenia (AWGS) criteria. CHD was identified via medical records or new diagnosed by at least two physicians. Depressive symptoms were assessed using the Geriatric Depression Scale (GDS) ≥11. Longitudinal data on new onset depressive symptoms were collected up to 12 months after baseline.Results: We found that 103 (11.5%) of the 897 participants without depressive symptoms at baseline had developed depressive symptoms. Participants were classified into mutually exclusive groups based on sarcopenia status and CHD: normal, CHD alone, sarcopenia alone, and co-occurring groups. A logistic regression showed that the CHD alone [odd ratios (OR) = 1.81, 95% confidence interval (CI) = 1.07-3.07]], sarcopenia alone (OR = 2.77, 95% CI = 1.24-6.16), and co-occurring (OR = 7.12, 95% CI = 2.73-18.61) had higher risk of depressive symptoms than the normal group after adjusting for the covariates.Conclusions: CHD and sarcopenia synergistically increase the risk of new onset depressive symptoms in older adults. Thus, older adults may require early detection, and appropriate interventions should be implemented.

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Section: Discussionsupporting

confidence: 94%

Section: Introductionmentioning

confidence: 99%

Sarcopenia and Coronary Heart Disease Synergistically Increase the Risk of New Onset Depressive Symptoms in Older Adults

Chen¹,

Han²,

Yu³

et al. 2020

Preprint

Self Cite

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“…Third, Chen et al . clarified that appendicular skeletal muscle mass/height 2 was a preventive factor for depressive symptoms, which was inconsistent with data by Hayashi et al . Namely, muscle mass itself, not physical performance, was closely associated with depressive symptoms by a prospective study.…”

contrasting

confidence: 62%

“…Second, Chen et al . carried out a prospective cohort study to examine the predictors of depressive symptoms over a 1‐year period in 691 older adults . They used the 30‐item version of the GDS, and the number of participants with a positive GDS score was 83.…”

mentioning

confidence: 99%

Sarcopenia and depressive mood in older adults

Kawada

2019

Geriatrics Gerontology Int

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“…These results were identical to the findings of previous longitudinal or cross-sectional studies on the association between depressive symptoms and sarcopenia. A recent prospective study ( n = 691) demonstrated that the incidence of depressive symptoms increased with some chronic diseases including sarcopenia, type 2 diabetes mellitus and cardiovascular disease and SMM was the most relevant protective factor among SMM, muscle strength and physical performance [38]. A meta-analysis comprising 15 observational studies denoted that sarcopenic patients were likely to present with depressive symptoms [31].…”

Section: Discussionmentioning

confidence: 99%

Association between Sarcopenia and Depression in Patients with Chronic Liver Diseases

Nishikawa

Enomoto

Iwata

et al. 2019

JCM

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Association between sarcopenia, as evaluated by grip strength (GS) and skeletal muscle mass (SMM), and depression, as evaluated by Beck Depression Inventory-2nd edition (BDI-II) in chronic liver diseases (CLDs, n = 414, average age = 61.5 years), was investigated. Study subjects were classified into four groups: Group A (n = 60), lower GS and lower SMM (sarcopenia); group B (n = 44), lower GS and higher SMM; group C (n = 100), higher GS and lower SMM; group D (n = 210), higher GS and higher SMM. Factors associated with BDI-II score ≥11 were examined. BDI-II score 0–10 (normal) was found in 284 (68.6%), 11–16 (minimal) in 76 (18.4%), 17–20 (mild) in 24 (5.8%), 21–30 (moderate) in 15 (3.6%), and ≥31 (severe) in 15 (3.6%). The average ± standard deviation BDI-II score in liver cirrhosis (LC) patients (10.2 ± 9.6, n = 152) was significantly higher than that in non-LC patients (7.4 ± 7.2, n = 262) (p = 0.0058). Univariate analysis identified three factors to be significantly associated with BDI-I score ≥11: Our classification (groups of A, B, C, and D) (p = 0.0259), serum albumin (p = 0.0445), and the presence of LC (p = 0.0157). Multivariate analysis revealed that only group A (p = 0.0074, group D as a reference) was significant. In conclusion, sarcopenia can be an independent predictor for depression in CLDs.

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Twelve-Month Incidence of Depressive Symptoms in Suburb-Dwelling Chinese Older Adults: Role of Sarcopenia

Cited by 35 publications

References 44 publications

Sarcopenia and Coronary Heart Disease Synergistically Increase the Risk of New Onset Depressive Symptoms in Older Adults

Sarcopenia and Coronary Heart Disease Synergistically Increase the Risk of New Onset Depressive Symptoms in Older Adults

Sarcopenia and depressive mood in older adults

Association between Sarcopenia and Depression in Patients with Chronic Liver Diseases

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