Twelve‐month evaluation of a novel mineral–organic adhesive material used to stabilize dental implants placed in oversized osteotomies in vivo in an animal model

Cochran, David L.; Jones, Archie A.; Sugita, Ryushiro; Brown, Michael C.; Prasad, Hari; Kay, George W.

doi:10.1111/clr.13899

Cited by 3 publications

(2 citation statements)

References 19 publications

(31 reference statements)

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“…Based on these findings, it may be argued that the overpacking of bone substitutes hindering access to necessary vasculature may be problematic, too [29]. However, a novel mineral-organic osteoconductive adhesive based on tetracalcium phosphate, phosphoserine and water has shown superior regenerative potential without displaying porosity upon placement [35].…”

Section: Discussionmentioning

confidence: 99%

In Vitro Handling Characteristics of a Particulate Bone Substitute for Ridge Preservation Procedures

Dahl,

Klär-Quarz,

Schulz

et al. 2024

Materials

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While particulate bone substitute materials are applied in a variety of augmentation procedures, standardized defects are being used for preclinical testing. This in vitro study evaluated the density and homogeneity of a particulate bone substitute in ridge preservation procedures. Premolars and molars were extracted in ten semimandibles of minipig cadavers. Light body impression material was used for determining the volume of the extraction sites followed by augmentation with particulate material, thereby weighing the graft material needed. Microradiographs and histologic sections were obtained for evaluating the homogeneity and density of the augmentation material. Statistical analyses were based on Shapiro–Wilk tests, Spearman’s rho and one sample Wilcoxon test followed by Bonferroni–Holm correction for multiple testing (α = 0.05). Based on 103 single alveoli evaluated, the mean volume determined was 0.120 cm3 requiring a mean amount of graft material of 0.155 g. With only three exceptions, all parameters (volume, mass of augmentation material, density and homogeneity) correlated significantly (p < 0.020). The apical parts of the alveoli showed reduced density as compared to the middle parts (p < 0.001) and the homogeneity of the augmentation material was also lower as compared to the middle (p < 0.001) and cervical parts (p </= 0.040). The packing of augmentation material is critical when non-standardized defects are treated.

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Section: Discussionmentioning

confidence: 99%

In Vitro Handling Characteristics of a Particulate Bone Substitute for Ridge Preservation Procedures

Dahl,

Klär-Quarz,

Schulz

et al. 2024

Materials

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“…They were able to show that the adhesive caused sufficient initial and later-implant stability. This might be based on a stepwise degeneration of the adhesive followed by sufficient osseointegration [36]. Other innovations focus on nest-like nanofiber structures to modify titanium implant surfaces and have been reported to improve osseointegration in animal models [37].…”

Section: Introductionmentioning

confidence: 99%

Osseointegration of a New, Ultrahydrophilic and Nanostructured Dental Implant Surface: A Comparative In Vivo Study

Pabst

Asran²,

Lüers³

et al. 2022

Biomedicines

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This study compared the osseointegration of acid-etched, ultrahydrophilic, micro- and nanostructured implant surfaces (ANU) with non-ultra-hydrophilic, microstructured (SA) and non-ultrahydrophilic, micro- and nanostructured implant surfaces (AN) in vivo. Fifty-four implants (n = 18 per group) were bilaterally inserted into the proximal tibia of New Zealand rabbits (n = 27). After 1, 2, and 4 weeks, bone-implant contact (BIC, %) in the cortical (cBIC) and spongious bone (sBIC), bone chamber ingrowth (BChI, %), and the supra-crestal, subperiosteal amount of newly formed bone, called percentage of linear bone fill (PLF, %), were analyzed. After one week, cBIC was significantly higher for AN and ANU when compared to SA (p = 0.01 and p = 0.005). PLF was significantly increased for ANU when compared to AN and SA (p = 0.022 and p = 0.025). After 2 weeks, cBIC was significantly higher in SA when compared to AN (p = 0.039) and after 4 weeks, no significant differences in any of the measured parameters were found anymore. Ultrahydrophilic implants initially improved osseointegration when compared to their non-ultrahydrophilic counterparts. In accordance, ultrahydrophilic implants might be appropriate in cases with a necessity for an accelerated and improved osseointegration, such as in critical size alveolar defects or an affected bone turnover.

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Multi-objective property optimisation of a phosphoserine-modified calcium phosphate cement for orthopaedic and dental applications using design of experiments methodology

Tzagiollari,

Redmond,

McCarthy

et al. 2024

Acta Biomaterialia

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Twelve‐month evaluation of a novel mineral–organic adhesive material used to stabilize dental implants placed in oversized osteotomies in vivo in an animal model

Cited by 3 publications

References 19 publications

In Vitro Handling Characteristics of a Particulate Bone Substitute for Ridge Preservation Procedures

In Vitro Handling Characteristics of a Particulate Bone Substitute for Ridge Preservation Procedures

Osseointegration of a New, Ultrahydrophilic and Nanostructured Dental Implant Surface: A Comparative In Vivo Study

Multi-objective property optimisation of a phosphoserine-modified calcium phosphate cement for orthopaedic and dental applications using design of experiments methodology

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