Turn-on Fluorescent Sensing of Glutathione <i>S</i>-Transferase at near-Infrared Region Based on FRET between Gold Nanoclusters and Gold Nanorods

Qin, Long; He, Xiwen; Chen, Langxing; Zhang, Yukui

doi:10.1021/acsami.5b00269

Cited by 104 publications

(39 citation statements)

References 59 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…reported on intracellular detection of mercury ions in a configuration using blue-emitting silsesquioxane polyhedral oligomeric donors to sensitize BSA-encapsulated 700 nm emitting AuNC acceptors (0.8 nm diameter, 25 atoms); sensitization was specifically ascribed to a FRET process in this case 30 . Similarly, Qin reported quenching interactions between glutathione-capped 2.4 nm AuNCs and gold nanorods as FRET as well 31 .…”

mentioning

confidence: 88%

Energy Transfer Sensitization of Luminescent Gold Nanoclusters: More than Just the Classical Förster Mechanism

Huston

Shabaev

et al. 2016

Sci Rep

View full text Add to dashboard Cite

Luminescent gold nanocrystals (AuNCs) are a recently-developed material with potential optic, electronic and biological applications. They also demonstrate energy transfer (ET) acceptor/sensitization properties which have been ascribed to Förster resonance energy transfer (FRET) and, to a lesser extent, nanosurface energy transfer (NSET). Here, we investigate AuNC acceptor interactions with three structurally/functionally-distinct donor classes including organic dyes, metal chelates and semiconductor quantum dots (QDs). Donor quenching was observed for every donor-acceptor pair although AuNC sensitization was only observed from metal-chelates and QDs. FRET theory dramatically underestimated the observed energy transfer while NSET-based damping models provided better fits but could not reproduce the experimental data. We consider additional factors including AuNC magnetic dipoles, density of excited-states, dephasing time, and enhanced intersystem crossing that can also influence ET. Cumulatively, data suggests that AuNC sensitization is not by classical FRET or NSET and we provide a simplified distance-independent ET model to fit such experimental data.

show abstract

mentioning

confidence: 88%

Energy Transfer Sensitization of Luminescent Gold Nanoclusters: More than Just the Classical Förster Mechanism

Huston

Shabaev

et al. 2016

Sci Rep

View full text Add to dashboard Cite

show abstract

“…The Raman scattering signals and the interaction between GNRs and Microcystis aeruginosa proteins was enhanced. The result is demonstrated by Qin Long et al 38,39 that the higher the concentration of protein or amino acid, the stronger the signal intensity.…”

Section: Resultsmentioning

confidence: 93%

Label-free and sensitive detection of microalgae protein using GNRs-based resonance light scattering system

Tang

Wang

et al. 2017

RSC Adv.

View full text Add to dashboard Cite

show abstract

“…In recent years, a large number of protein-sensing methods based on functionalized fluorescent AuNCs have been developed [101][102][103][104][105][106][107][108][109]. These sensors possess both superior selectivity to target proteins and exceptional optical properties.…”

Section: Detection Of Proteinsmentioning

confidence: 99%

Fluorescent Gold Nanoclusters: Promising Fluorescent Probes for Sensors and Bioimaging

Wang

Zhu

2017

J. Anal. Test.

View full text Add to dashboard Cite

Fluorescent gold nanoclusters (AuNCs) have recently emerged as a novel kind of promising fluorescent probes for high-performance sensors and bioimaging because of their ultrasmall size (\3 nm), strong luminescence, good photostability, and excellent biocompatibility. Over the past decade, we have witnessed growing popularity of AuNCs in analytical applications and enormous efforts have been devoted to their development. In this review, we provide an update on recent advances in the development of AuNCs in terms of physicochemical properties, synthesis strategies, and bioapplications. The optical, electrochemical, catalytical, and solvatochromic properties of AuNCs are first summarized, which are followed by different ligands or template-assisted controllable synthetic methods. Afterwards functionalization of AuNCs is described in terms of ligand exchange, bioconjugation, and noncovalent interaction. We then focus on the applications of AuNCs as fluorescent probes for detection of metal ions, inorganic anions, small biomolecules, proteins, nucleic acids, drug molecules, pH, and temperature. We also summarize the usage of metal NCs in cellular and in vivo targeting and imaging. Finally, we conclude with a brief look at the future challenges and prospects of the development of AuNCs.

show abstract

Turn-on Fluorescent Sensing of Glutathione S-Transferase at near-Infrared Region Based on FRET between Gold Nanoclusters and Gold Nanorods

Cited by 104 publications

References 59 publications

Energy Transfer Sensitization of Luminescent Gold Nanoclusters: More than Just the Classical Förster Mechanism

Energy Transfer Sensitization of Luminescent Gold Nanoclusters: More than Just the Classical Förster Mechanism

Label-free and sensitive detection of microalgae protein using GNRs-based resonance light scattering system

Fluorescent Gold Nanoclusters: Promising Fluorescent Probes for Sensors and Bioimaging

Contact Info

Product

Resources

About