Turmeric Extract-loaded Selenium Nanoparticles Counter Doxorubicin-induced
Hepatotoxicity in Mice via Repressing Oxidative Stress, Inflammatory Cytokines, and
Cell Apoptosis
Barakat M. ALRashdi,
Mohamed M. Hussein,
Rawan M. Mohammed
et al.
Abstract:Background::
Doxorubicin (DOX) is an antitumor anthracycline used to treat a variety of malignancies;
however, its clinical use is associated with noticeable hepatotoxicity. Therefore, the current study was designed
to delineate if biosynthesized SeNPs with turmeric extract (Tur-SeNPs) could alleviate DOX-induced
hepatic adverse effects.
Methods::
Mice were orally post-treated with Tur extract, Tur-SeNPs, or N-acetyl cysteine after the intraperitoneal
injection of DOX.
objective:
Therefore, the current stu… Show more
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