Turmeric: A Review of Its Chemical Composition, Quality Control, Bioactivity, and Pharmaceutical Application

Meng, Fan-Cheng; Zhou, Yanqing; Ren, Diandong; Wang, Ruibing; Wang, Chunming; Lin, Ligen; Zhang, Xiaoqi; Ye, Wen‐Cai; Zhang, Qingwen

doi:10.1016/b978-0-12-811518-3.00010-7

Cited by 35 publications

(47 citation statements)

References 212 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These characteristics make C. longa rhizome ideal for gastronomy. Especially, it is the principal ingredient of curry, for which it is probably popularly known [ 14 , 15 , 16 ].…”

Section: Introductionmentioning

confidence: 99%

Curcuma longa L. Rhizome Essential Oil from Extraction to Its Agri-Food Applications. A Review

Ibáñez

Blázquez

2020

Plants

View full text Add to dashboard Cite

Curcuma longa L. rhizome essential oil is a valuable product in pharmaceutical industry due to its wide beneficial health effects. Novel applications in the agri-food industry where more sustainable extraction processes are required currently and safer substances are claimed for the consumer are being investigated. This review provides information regarding the conventional and recent extraction methods of C. longa rhizome oil, their characteristics and suitability to be applied at the industrial scale. In addition, variations in the chemical composition of C. longa rhizome and leaf essential oils regarding intrinsic and extrinsic factors and extraction methods are also analysed in order to select the most proper to obtain the most efficient activity. Finally, the potential applications of C. longa rhizome oil in the agri-food industry, such as antimicrobial, weedicide and a food preservative agent, are included. Regarding the data, C. longa rhizome essential oil may play a special role in the agri-food industry; however, further research to determine the application threshold so as not to damage crops or affect the organoleptic properties of food products, as well as efficient encapsulation techniques, are necessary for its implementation in global agriculture.

show abstract

“…These characteristics make C. longa rhizome ideal for gastronomy. Especially, it is the principal ingredient of curry, for which it is probably popularly known [ 14 , 15 , 16 ].…”

Section: Introductionmentioning

confidence: 99%

Curcuma longa L. Rhizome Essential Oil from Extraction to Its Agri-Food Applications. A Review

Ibáñez

Blázquez

2020

Plants

View full text Add to dashboard Cite

show abstract

“…In traditional Chinese medicine, it is called “Jianghuang”, and has been widely used for the treatment of diabetic wounds, hepatic disorders and cardiovascular disease [ 1 ]. Phytochemical investigation of turmeric has revealed it contains curcuminoids and volatile oils as the major components [ 2 ]. Curcumin and two demethoxy derivatives, demethoxycurcumin and bisdemethoxycurcumin, are the major curcuminoids in turmeric, which have anti-cancer, anti-inflammatory, neuroprotective, anti-Alzheimers and anti-oxidant activities [ 2 , 3 , 4 , 5 , 6 , 7 , 8 ].…”

Section: Introductionmentioning

confidence: 99%

Simultaneous Quantification of Three Curcuminoids and Three Volatile Components of Curcuma longa Using Pressurized Liquid Extraction and High-Performance Liquid Chromatography

Chao

Wang

et al. 2018

Molecules

Self Cite

View full text Add to dashboard Cite

A high-performance liquid chromatography (HPLC) method was investigated for the simultaneous quantification of two chemical types of bioactive compounds in the rhizome of Curcuma longa Linn. (turmeric), including three curcuminoids: Curcumin, bisdemethoxycurcumin, and demethoxycurcumin; and three volatile components: ar-turmerone, β-turmerone, and α-turmerone. In the present study, the sample extraction system was optimized by a pressurized liquid extraction (PLE) process for further HPLC analysis. The established HPLC analysis conditions were achieved using a Zorbax SB-C18 column (250 mm × 4.6 mm i.d., 5 μm) and a gradient mobile phase comprised of acetonitrile and 0.4% (v/v) aqueous acetic acid with an eluting rate of 1.0 mL/min. The curcuminoids and volatile components were detected at 430 nm and 240 nm, respectively. Moreover, the method was validated in terms of linearity, sensitivity, precision, stability and accuracy. The validated method was successfully applied to evaluate the quality of twelve commercial turmeric samples.

show abstract

Section: Natural Health Products Natural Compounds and Natural Ementioning

confidence: 99%

“…The Curcuma longa plant is primarily composed of curcuminoids and essential oils [ 176 ]. The primary curcuminoid is curcumin which displays anti-cancer activities through the anti-oxidative and anti-inflammatory pathways mentioned above, but other curcuminoids such as demethoxycurcumin and bisdemethoxycurcumin exist within this plant as well [ 176 , 177 ]. The active ingredients in the essential oil include ar-turmerone, α-turmerone, and β-turmerone which also show anti-cancer effects through anti-inflammatory and anti-oxidative pathways [ 176 ].…”

Section: Natural Health Products Natural Compounds and Natural Ementioning

confidence: 99%

Natural Health Products (NHP’s) and Natural Compounds as Therapeutic Agents for the Treatment of Cancer; Mechanisms of Anti-Cancer Activity of Natural Compounds and Overall Trends

Scaria

Sood

Raad

et al. 2020

IJMS

View full text Add to dashboard Cite

Most cancer therapeutics, such as tubulin-targeting chemotherapy drugs, cause cytotoxic, non-selective effects. These harmful side-effects drastically reduce the cancer patient’s quality of life. Recently, researchers have focused their efforts on studying natural health products (NHP’s) which have demonstrated the ability to selectively target cancer cells in cellular and animal models. However, the major hurdle of clinical validation remains. NHP’s warrant further clinical investigation as a therapeutic option since they exhibit low toxicity, while retaining a selective effect. Additionally, they can sensitize cancerous cells to chemotherapy, which enhances the efficacy of chemotherapeutic drugs, indicating that they can be utilized as supplemental therapy. An additional area for further research is the investigation of drug–drug interactions between NHP’s and chemotherapeutics. The objectives of this review are to report the most recent results from the field of anticancer NHP research, and to highlight the most recent advancements in possible supplemental therapeutic options.

show abstract

Turmeric: A Review of Its Chemical Composition, Quality Control, Bioactivity, and Pharmaceutical Application

Cited by 35 publications

References 212 publications

Curcuma longa L. Rhizome Essential Oil from Extraction to Its Agri-Food Applications. A Review

Curcuma longa L. Rhizome Essential Oil from Extraction to Its Agri-Food Applications. A Review

Simultaneous Quantification of Three Curcuminoids and Three Volatile Components of Curcuma longa Using Pressurized Liquid Extraction and High-Performance Liquid Chromatography

Natural Health Products (NHP’s) and Natural Compounds as Therapeutic Agents for the Treatment of Cancer; Mechanisms of Anti-Cancer Activity of Natural Compounds and Overall Trends

Contact Info

Product

Resources

About