Neutralatmosphere turbulence exists almost ubiquitously throughout the atmosphere up to heights of about 100 km, and then completely disappears above about 120 km altitude. It's importance in providing coupling in the lower regions of the atmosphere (troposphere and stratosphere) is well known, but its importance for coupling between the middle atmosphere and ionosphere is not so well understood. In this review, we will concentrate on the role that turbulence plays in the coupling between the middle atmosphere and the low levels of the ionosphere. The discussion will include a review of some of the important principles of turbulence, as well as some of the unique features about middle atmospheric turbulence.A detailed collection of measurements of turbulent eddy diffusion coefficients will be presented, along with some warnings about how these data should be interpreted. The need to understand turbulence at a very fundamental level in order to apply measurements of such "diffusion coefficients" is stressed.