Tuning thermal gelling behavior of N-isopropylacrylamide based copolymer through introducing cucurbit[8]uril ternary complex on side-chain

Preparation of dyed polymer microspheres by a physical–chemical dual-binding method and their application in lateral flow immunoassay

“…The bifunctional polymer microspheres were synthesized by soap-free emulsion polymerization, using water as a solvent, NaSS as an active emulsifier and KPS as an initiator. As illustrated in Scheme 1(b), based on the organic reaction of chloromethyl and phenolic hydroxyl groups, 37 in order to undergo a covalent binding reaction during the swelling process, dyes containing phenolic hydroxyl groups in the molecular structure were preferentially selected because dyes were rich in variety, diverse in color, cheap and easy to obtain. This method consisted of three parts: (1) mixing the polymer microspheres and the dye molecules; (2) swelling the microspheres at high temperature along with the covalent bonding reaction between microspheres and dyes and (3) deswelling the microspheres with removal of the swelling agent, thereby encapsulating the dye inside and on the surface of the polymer microspheres.…”

“…VBC , a bifunctional monomer, was easy to undergo nucleophilic substitution reactions with many substances due to the high chemical activity of its chloromethyl group. 37 As illustrated in Scheme 2, the aim of adding VBC was mainly to provide chloromethyl for polymer microspheres. The dye molecules could not only be introduced into the microspheres by swelling, but also be combined on the surface and inside of the microspheres through chemical reactions.…”

“…The dye molecules could not only be introduced into the microspheres by swelling, but also be combined on the surface and inside of the microspheres through chemical reactions. 37 However, with the gradual increase of the VBC ratio, the molecular weight of the obtained microspheres may change greatly, which may affect the speed of dye molecules dissolving into the microspheres. Therefore, the amount of incorporation in the final microspheres changed as above.…”

Polymeric self-assembled cucurbit[n]urils: Synthesis, structures and applications

“…Tan et al . employed a N -isopropylacrylamide-based copolymer bearing naphthyl groups on its side chains in combination with methyl viologen and Q [8] to afford a red solution [147] . 1 H NMR spectra indicated that viologen and naphthyl groups were encapsulated within the Q [8] cavities.…”

Tunable Fluorescence-Responsive Double Hydrophilic Block Polymers Induced by the Formation of Pseudopolyrotaxanes with Cucurbit[7]Uril

“…Cucurbit[n]urils (Q[n]s or CB[n]s), a family of a new class of synthetic macrocyclic host molecules, have drawn increasing attention in supramolecular chemistry and materials science [47,48]. Their popularity stems from their good selectivity and strong binding affinity with a range of guest molecules in aqueous solution [49,50,51,52]. Among CB[n]s, CB[7] presents high water solubility (ca.…”