Tuning the Topography of Dynamic 3D Scaffolds through Functional Protein Wrinkled Coatings
Elizabeth Oguntade,
Daniel Fougnier,
Sadie Meyer
et al.
Abstract:Surface wrinkling provides an approach to fabricate micron and sub-micron-level biomaterial topographies that can mimic features of the dynamic, in vivo cell environment and guide cell adhesion, alignment, and differentiation. Most wrinkling research to date has used planar, two-dimensional (2D) substrates, and wrinkling work on three-dimensional (3D) structures has been limited. To enable wrinkle formation on architecturally complex, biomimetic 3D structures, here, we report a simple, low-cost experimental wr… Show more
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