Tuning the Biodegradation Rate of Silk Materials via Embedded Enzymes
Junqi Wu,
Kareen A. Fajardo Cortes,
Chunmei Li
et al.
Abstract:Conventional thinking when designing biodegradable materials and devices is to tune the intrinsic properties and morphological features of the material to regulate their degradation rate, modulating traditional factors such as molecular weight and crystallinity. Since regenerated silk protein can be directly thermoplastically molded to generate robust dense silk plastic-like materials, this approach afforded a new tool to control silk degradation by enabling the mixing of a silk-degrading protease into bulk si… Show more
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