Tunable ZnO spheres with high anti-biofilm and antibacterial activity via a simple green hydrothermal route

Patrinoiu, Greta; Calderón-Moreno, José Maria; Chifiriuc, Mariana Carmen; Saviuc, Crina; Bı̂rjega, R.; Carp, Oana

doi:10.1016/j.jcis.2015.09.059

Cited by 45 publications

(25 citation statements)

References 95 publications

(85 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The Si and F modified coatings reduced the bacterial adhesion by 68% at 12 h compared with stainless steel [46]. A number of doped/co-doped photocatalytic materials were also reported [42,[47][48][49][50][51][52][53][54] to show antibacterial action. However, a direct comparison of the efficiency of these catalysts is not possible due to the lack of a standard testing protocol.…”

Section: Resultsmentioning

confidence: 97%

Antibacterial properties of F-doped ZnO visible light photocatalyst

Podporska-Carroll

Myles

Quilty

et al. 2017

Journal of Hazardous Materials

202

View full text Add to dashboard Cite

Section: Resultsmentioning

confidence: 97%

Antibacterial properties of F-doped ZnO visible light photocatalyst

Podporska-Carroll

Myles

Quilty

et al. 2017

Journal of Hazardous Materials

202

View full text Add to dashboard Cite

“…US FDA has enlisted ZnO as GRAS (generally recognized as safe) metal oxide. 6,7 The presence of bioactive compounds in plants, algae, and microorganisms has made them a good candidate for the synthesis of nanoparticles (NPs). 8 Cyanobacteria as a group of ancient and abundant microorganisms with prokaryotic cell structures have the capability of carbon dioxide-dependent photosynthesis.…”

Section: Introductionmentioning

confidence: 99%

“…EA03, (3) synthesis of ZnO NPs using the cell extract of Nostoc sp. EA03, (4) characterization of the CEN-ZnO NPs, (5) assessment of the antibacterial, anti-biolm and antifungal activities of different concentrations of CEN-ZnO NPs against three important clinical bacterial isolates including E. coli 25922, P. aeruginosa PAO1, and S. aureus 25923, (6) in vitro analysis of cytotoxic effect of CEN-ZnO NPs on human lung broblast cells MRC-5 and the cancerous human lung alveolar epithelial cells A549, (7) the measurement of reactive oxygen species (ROS) levels in tested bacterial cells aer exposure to different concentrations of CEN-ZnO.…”

Section: Introductionmentioning

confidence: 99%

A bio-inspired strategy for the synthesis of zinc oxide nanoparticles (ZnO NPs) using the cell extract of cyanobacterium Nostoc sp. EA03: from biological function to toxicity evaluation

et al. 2019

View full text Add to dashboard Cite

Cyanobacteria, as one of the largest groups of phototrophic bacteria, have a high potential as an excellent source of fine chemicals and bioactive compounds, including lipid-like compounds, amino acid derivatives, proteins, and pigments. This study aimed to synthesize ZnO nanoparticles using the cell extract of the cyanobacterium Nostoc sp. EA03 (CEN-ZnO NPs) through a rapid and eco-friendly approach. The biosynthesized nanoparticles, CEN-ZnO NPs, were characterized by UV-Vis spectroscopy, X-ray diffraction (XRD), zeta potential measurement, differential scanning calorimetry (DSC)/thermogravimetric analysis (TGA), FTIR, SEM, TEM, and EDX spectroscopy. The UV-Vis spectrum showed an absorption peak at 370 nm. The star-shaped CEN-ZnO NPs, as observed in the TEM and SEM images, had an average diameter of 50-80 nm. MIC and MBC values for E. coli, P. aeruginosa and S. aureus, were determined to be, respectively, 2000, 2000, and 64 mg ml À1 , and 2500, 2500 and 128 mg ml À1 . Further analysis through confocal laser scanning microscopy (CLSM) provided the observable confirmation that the CEN-ZnO NPs stunted the bacterial growth, preventing the formation of exopolysaccharides. The AFM analysis of surface topography of bacterial biofilm samples treated with CEN-ZnO NPs showed a rugged topography in some parts of the biofilm surface, indicating the destruction of biofilms. In contrast, in the untreated control samples, the structured biofilms were flat and prominent. MTT assay indicated that CEN-ZnO NPs had less cytotoxicity on the MRC-5 lung fibroblast cells compared with the cancerous treated A549 cells. As the concentration of the CEN-ZnO NPs increased, the amount of ROS produced in the tested bacterial strains also increased. Analyzing the data obtained from flow cytometry showed that the higher concentrations of CEN-ZnO NPs lead to a reduction in the viability of P. aeruginosa PAO1, E. coli and S. aureus. The biosynthesized ZnO nanoparticles using Nostoc cell extracts exhibited different attributes, inspiring enough to be considered for further investigation.

show abstract

“…In this regard, the hybrid nanosystems based on magnetite nanoparticles (MGNPs) could represent an alternative, considering their accessible and versatile preparation, reduced toxicity as well as antimicrobial properties [ 13 , 14 , 15 , 16 ]. MGNPs were authorized as in vivo drug delivery platform, and as a result, several loaded systems with a good antimicrobial activity were recently reported [ 17 , 18 , 19 , 20 , 21 , 22 , 23 ].…”

Section: Introductionmentioning

confidence: 99%

Anti-biofilm Fe3O4@C18-[1,3,4]thiadiazolo[3,2-a]pyrimidin-4-ium-2-thiolate Derivative Core-shell Nanocoatings

et al. 2020

View full text Add to dashboard Cite

The derivatives 5,7-dimethyl[1,3,4]thiadiazolo[3,2-a]pyrimidin-4-ium-2-thiolate (1) and 7-methyl-5-phenyl[1,3,4]thiadiazolo[3,2-a]pyrimidin-4-ium-2-thiolate (2) were fully characterized by single-crystal X-ray diffraction. Their supramolecular structure is built through both π–π stacking and C=S–π interactions for both compounds. The embedment of the tested compounds into Fe3O4@C18 core-shell nanocoatings increased the protection degree against Candida albicans biofilms on the catheter surface, suggesting that these bioactive nanocoatings could be further developed as non-cytotoxic strategies for fighting biofilm-associated fungal infections.

show abstract

Tunable ZnO spheres with high anti-biofilm and antibacterial activity via a simple green hydrothermal route

Cited by 45 publications

References 95 publications

Antibacterial properties of F-doped ZnO visible light photocatalyst

Antibacterial properties of F-doped ZnO visible light photocatalyst

A bio-inspired strategy for the synthesis of zinc oxide nanoparticles (ZnO NPs) using the cell extract of cyanobacterium Nostoc sp. EA03: from biological function to toxicity evaluation

Anti-biofilm Fe3O4@C18-[1,3,4]thiadiazolo[3,2-a]pyrimidin-4-ium-2-thiolate Derivative Core-shell Nanocoatings

Contact Info

Product

Resources

About