We demonstrate a flexible, electrowetting-driven, variable-focus liquid microlens. The microlens is fabricated using a soft polymer polydimethylsiloxane. The lens can be smoothly wrapped onto a curved surface. A low-temperature fabrication process was developed to reduce the stress on and to avoid any damage to the polymer. The focal length of the microlens varies between À15.0 mm to þ28.0 mm, depending on the applied voltage. The resolving power of the microlens is 25.39 line pairs per mm using a 1951 United States Air Force resolution chart. The typical response time of the lens is around 50 ms. V C 2012 American Institute of Physics.[http://dx.doi.org/10.1063/1.4726038]Microlenses are important components in modern miniaturized optical systems.1-9 Among these microlenses, emerging liquid-based variable-focus microlenses are of special importance, because they do not require complicated mechanical systems to adjust optical performance, and they are widely used in photonics, display and biomedical systems.1-4 Meanwhile, microlenses made on flexible and curved substrates could have significant advantages over microlenses on flat substrates in improving the field of view (FOV) 5,6 and creating three-dimensional (3-D) effect. 7,8 For example, microlenses have been fabricated on spherical surfaces as artificial compound eyes.9,10 Current microlenses can be either tunable in focus [1][2][3][4] or made on curved surfaces, 9,11 but not both. Pressure-based variable-focus microlenses require an external mechanical control system and are difficult to be extended to a lens array.12 Tunable lenses based on phase modulation have relatively small magnitude of change in the focal length due to material properties. 13 It was previously reported that variablefocus liquid microlenses actuated by thermo-sensitive hydrogel could be formed on curved surfaces.6 However, they have complicated structures and suffer long response time due to their actuation mechanisms. Robustness and quick response are both of importance to any optical system. Benefitting from short response time, low electrical power consumption, compact structure and the robustness under voltage cycling, electrowetting-driven liquid microlenses have drawn much attention and have been commercialized. 1,14-16 However, traditional electrowetting microlenses are normally fabricated on rigid substrates, such as glass, silicon, and polyethylene terephthalate, 1,14-17 and are consequently not compatible with curved surfaces. Flexible electrowetting microlenses could bring electrowetting lenses into a broader field of applications.Here, we present an electrowetting-driven liquid microlens fabricated on a flexible polymer polydimethylsiloxane (PDMS). The lens has a thin soft polymer substrate, which can be smoothly wrapped on a curved surface, e.g., spherical or cylindrical surfaces. As demonstration, a lens has been made on the surface of a contact lens to show its flexibility. We also describe the processing steps and the materials used for a low-temperature fabrication pr...