Tumor thrombus arising from malignancies has been well recognized by both anatomic and metabolic imaging modalities, including FDG-PET. Recently, venous thromboembolism accumulating FDG has also been reported by a few literatures. However, blood thrombus accumulating radioiodine has never been reported by now. This case presents a follicular thyroid carcinoma patient with venous thromboembolism in the left brachiocephalic vein and superior vena cava, which could accumulate both FDG and radioiodine, mimicking thyroid carcinoma extension.