1995
DOI: 10.1007/bf00194691
|View full text |Cite
|
Sign up to set email alerts
|

Tumour infiltrating T-cells in gastric lymphoma

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
2

Citation Types

1
3
0

Year Published

1999
1999
2004
2004

Publication Types

Select...
4

Relationship

0
4

Authors

Journals

citations
Cited by 4 publications
(4 citation statements)
references
References 19 publications
1
3
0
Order By: Relevance
“…T lymphocytes were diffusely infiltrating the mucosal layer and intermingling among the lymphoma cells, as reported previously 21–23,25 , 28–32 . We support that infiltrating T cells may play a role in pathogenesis of MALT lymphoma.…”
Section: Discussionsupporting
confidence: 90%
See 1 more Smart Citation
“…T lymphocytes were diffusely infiltrating the mucosal layer and intermingling among the lymphoma cells, as reported previously 21–23,25 , 28–32 . We support that infiltrating T cells may play a role in pathogenesis of MALT lymphoma.…”
Section: Discussionsupporting
confidence: 90%
“…The response of low‐grade B‐cell gastric MALT lymphomas to stimulating strains of H. pylori is dependent on H. pylori ‐specific T cells and their products rather than the bacteria themselves 1,21–24 . Yoshino and Akagi reported that autoreactive B cells proliferate in response to H. pylori ‐specific T cells, presumably with some cytokines 25 .…”
Section: Discussionmentioning
confidence: 99%
“…2,3 Low-grade MALT lymphoma is initially confined to the gastric mucosa, and its growth depends critically on the contact help of H pylori-specific intratumoral T cells; therefore, it responds favorably to H pylori eradication therapy. [4][5][6] However, when the lymphoma invades the deep layers of the gastric wall and disseminates to local lymph nodes and distal sites, the tumor loses its dependence on H pylori-specific T cells and is no longer sensitive to H pylori eradication therapy. [7][8][9] Finally, low-grade gastric MALT lymphoma may transform into a more aggressive diffuse large B-cell lymphoma (DLBCL).…”
Section: Introductionmentioning
confidence: 99%
“…[7][8][9] Finally, low-grade gastric MALT lymphoma may transform into a more aggressive diffuse large B-cell lymphoma (DLBCL). 10,11 Direct 12-14 and indirect antigen stimulation 4,5 and several genetic factors, including genetic instability, 15 trisomy 3, 16 p53 mutation/LOH, 17 p16 deletion, 18 t(1;14)(p22;q32), 19 and t(11; 18)(q21;q21), 20,21 are implicated in MALT lymphoma development. However, the molecular events underlying the multistep progression of the tumor remain largely unknown.…”
Section: Introductionmentioning
confidence: 99%