1935
DOI: 10.1097/00000441-193503000-00023
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Tumors of the Female Pelvic Organs

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Cited by 66 publications
(25 citation statements)
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“…irritation of peritoneum from the tumor, obstruction of the lymphatics by the tumor, fluid secretion by the tumor from increased permeability of neovasculature, secondary to torsion of the pedicle of the tumor itself, low serum proteins and release of toxins and inflammatory products [2][3][4][5][6]. The fluid in the chest in these patients originates from the fluid in the abdomen as has been determined by injecting dye into the ascites, which appears in the pleural effusions in about 3 h [7].…”
Section: Review Of Literaturementioning
confidence: 99%
“…irritation of peritoneum from the tumor, obstruction of the lymphatics by the tumor, fluid secretion by the tumor from increased permeability of neovasculature, secondary to torsion of the pedicle of the tumor itself, low serum proteins and release of toxins and inflammatory products [2][3][4][5][6]. The fluid in the chest in these patients originates from the fluid in the abdomen as has been determined by injecting dye into the ascites, which appears in the pleural effusions in about 3 h [7].…”
Section: Review Of Literaturementioning
confidence: 99%
“…It was first described by Meigs in 1934 in a series of three cases. [1] It was designated as “Meigs syndrome” by Rhodes and Terrel in 1937. [2] Ovarian tumor can be a fibroma, myxofibroma, fibromyxoma, thecoma or a granulose cell tumor.…”
Section: Discussionmentioning
confidence: 99%
“…In the 1930s, Meigs, an American gynecologist, was the first to advocate cytoreductive surgery followed by adjuvant radiotherapy in patients with ovarian cancer, a disease with a very high propensity to disseminate to the peritoneum. 37 The survival rate after cytoreductive surgery for the treatment of ovarian cancer, however, remained poor. As a result, treatment of ovarian cancer mainly depended on chemotherapy, and surgical strategies were not optimized until the late 1960s and 1970s, when Munnell and Griffiths independently demonstrated that better survival rates could be achieved by more extensive surgery with the size of residual disease being the most important prognostic factor.…”
Section: Historical Perspective Of Cytoreductive Surgerymentioning
confidence: 99%