Tumors of the Eye and Ocular Adnexal Tissues

Rebhun, W C

doi:10.1016/s0749-0739(17)30188-8

Cited by 49 publications

(47 citation statements)

References 43 publications

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“…Intraocular tumours are rare in horses (Rebhun 1998). Uveal melanoma is the most frequent intraocular neoplasia in the horse, albeit it is an uncommon condition (Rebhun 1998).…”

Section: Discussionmentioning

confidence: 99%

“…Uveal melanoma is the most frequent intraocular neoplasia in the horse, albeit it is an uncommon condition (Rebhun 1998). Lymphosarcoma, adenoma and adenocarcinoma are other very uncommon intraocular tumours in horses and benign proliferative optic neuropathy has also been reported in older horses (Rebhun 1998). Beside these tumours derived from mature tissues, intraocular tumours derived from primitive medullary epithelium including medulloepithelioma and retinoblastoma should also be considered (Rebhun 1998).…”

Section: Discussionmentioning

confidence: 99%

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Rapidly growing primary malignant teratoid medulloepithelioma of the ciliary body in a gelding

Bergen

Vries

Ducatelle

et al. 2014

Vet Record Case Reports

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Intraocular medulloepithelioma is a relatively rare tumour in horses which is difficult to differentiate from retinoblastoma. The rate of growth of this tumour has not been investigated so far. We present a case of a primary intraocular teratoid malignant medulloepithelioma in a four-year-old gelding that was unilaterally blind at presentation. Repeated examination revealed rapid growth of the tumour. After enucleation of the affected eye, the horse returned to its former level of performance without recurrence for 12 months postoperatively. The histological and immunohistochemical examination of the mass clearly confirmed the malignancy of the tumour. Clinicians should be aware of the potential malignant behaviour of intraocular neoplasias. Immunohisto chemistry plays an important role in the final diagnosis

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“…Intraocular tumours are rare in horses (Rebhun 1998). Uveal melanoma is the most frequent intraocular neoplasia in the horse, albeit it is an uncommon condition (Rebhun 1998).…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Rapidly growing primary malignant teratoid medulloepithelioma of the ciliary body in a gelding

Bergen

Vries

Ducatelle

et al. 2014

Vet Record Case Reports

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“…Reports of 90 Sr‐β plesiotherapy in veterinary ophthalmology include its use in the treatment of canine corneal SCC 15 and conjunctival hemangiosarcoma, 16 equine corneal and conjunctival SCC, 17–19 and equine perilimbal angiosarcoma 20 . The radiation dosages and optimal radiation delivery protocols for conjunctival tumors in dogs have not been established.…”

Section: Discussionmentioning

confidence: 99%

Canine limbal melanoma: 30 cases (1992–2004). Part 2. Treatment with lamellar resection and adjunctive strontium‐90β plesiotherapy – efficacy and morbidity

Donaldson¹,

Sansom²,

Adams

2006

Veterinary Ophthalmology

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Lamellar resection and adjunctive 90Sr-beta plesiotherapy is relatively easy to perform, is minimally invasive, and extremely well tolerated by patients. The treatment is highly efficacious in the management of canine limbal melanoma. Modification of the radiation dosimetry, in particular reducing the total dose of radiation and the dose per radiation fraction, is necessary to reduce the incidence of late onset side effects.

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“…There are numerous reports of lymphoma affecting the eye (Murphy et al . ; Rebhun ; D'Agostino and Brightman ; Bosch and Klein ; Germann et al . ; Rendle et al .…”

Section: Introductionmentioning

confidence: 99%

Recurrent adnexal lymphoma in a horse

Martabano

Brooks

Whitley

et al. 2017

Equine Veterinary Education

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Summary Lymphoma is a relatively uncommon neoplasm in the horse; however, it is considered the most common neoplasia of the equine haemolymphatic system. Limited reports of adnexal lymphoma have been documented in the literature, with no known reports of recurrence nearly a decade after mass excision. The objective is to describe a case of recurrent adnexal lymphoma in a 20‐year‐old Quarter Horse gelding presented to the Ophthalmology service at the University of Florida Veterinary Hospital (UFVH) for evaluation of a solitary subconjunctival mass of the right eye (OD). A focal, pink, fleshy mass associated with the dorsomedial bulbar conjunctiva was noted. An excisional biopsy was performed. Histopathology revealed lymphoma with clean margins. The client declined staging and further therapy at the initial visit. Approximately 8 years later, the horse began to exhibit intermittent mild to moderate diffuse swelling of the conjunctiva OD. Six months after onset, the swelling worsened acutely and was accompanied by severe swelling of the left conjunctiva (OS). The horse then returned to UFVH and was diagnosed with diffuse, bilateral conjunctival lymphoma. Humane euthanasia was elected. T cell lymphoma was confirmed with immunohistochemistry performed post‐mortem. At necropsy, neoplastic tissue was observed throughout the adnexal and ocular tissues of both eyes and in the submandibular lymph nodes. Adnexal lymphoma is an uncommon neoplasm in the horse. To the authors’ knowledge, this is the first documentation of a nodular adnexal lymphoma that involved an 8‐year period without recurrence followed by development of diffuse, bilateral disease. Typically, surgical excision of the nodular form of lymphoma involving the extraocular tissues yields an improved prognosis compared with the diffuse form of the disease. Further investigation is necessary to determine if nodular forms of adnexal lymphoma represent early stages of diffuse extraocular or systemic disease.

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Tumors of the Eye and Ocular Adnexal Tissues

Cited by 49 publications

References 43 publications

Rapidly growing primary malignant teratoid medulloepithelioma of the ciliary body in a gelding

Rapidly growing primary malignant teratoid medulloepithelioma of the ciliary body in a gelding

Canine limbal melanoma: 30 cases (1992–2004). Part 2. Treatment with lamellar resection and adjunctive strontium‐90β plesiotherapy – efficacy and morbidity

Recurrent adnexal lymphoma in a horse

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