Tumors of Peripheral Nerves

Lewis, Dean; Hart, Deryl

doi:10.1097/00000658-193012000-00001

Cited by 53 publications

(8 citation statements)

References 0 publications

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“…forearm) often present as a visible mass or they can be palpated (14/16). The mass can easily be mobilized from side to side but not along the axis of the extremity [8]. In most cases a peripheral nerve neurinoma causes pain or paraesthesia in the territory of its parent nerve, either spontaneously or on palpation or tapping.…”

Section: Diagnosismentioning

confidence: 99%

Peripheral nerve schwannomas ? an analysis of 16 patients

1997

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16 patients with peripheral nerve neurinomas (benign schwannomas) were operated upon in our hospital between 1990-1995. The largest tumours were found on proximal segments of peripheral nerves (brachial plexus: 15 cm, sciatic nerve: 20 cm). The average duration of symptoms was 1 1/2 years (range: 3 months-15 years). Pain or painful paraesthesias were the main complaints (13/16). Postoperatively, 9 patients were painfree while 4 improved. Similarly, neurological deficits were favourably influenced by the operation: Out of 5 patients with motor deficits 4 had complete, 1 patient had partial recovery. One out of 4 patients with sensory deficits had complete recovery, 2 remained unchanged, while 1 worsened. Two patients developed new motor and 6 patients new sensory deficits, which (in the course of time) did not disappear completely. New deficits developed predominantly in patients with large tumours or longstanding symptoms. Tumour recurrences were not seen during the follow-up period of 23 months. Our findings revealed that in the majority of cases peripheral nerve neurinomas can be excised with good results. Patients should be treated by a neurosurgeon with special expertise in peripheral nerve surgery. The patient should be thoroughly informed pre-operatively about any eventual new neurological deficits following surgery.

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Section: Diagnosismentioning

confidence: 99%

Peripheral nerve schwannomas ? an analysis of 16 patients

1997

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“…Review of the English literature revealed 12 documented cases. [4][5][6][7][8][9][10][11][12][13][14] The salient clinical features of these cases and of the one reported in this paper are given in Table 1. In addition to these 12 cases, brief reference to another seven cases of ganglioneu-roblastoma was made: four in the retroperitoneum, 2 one in the neck, 2 and two in the posterior mediastinum.…”

Section: Discussionmentioning

confidence: 99%

“…2,3 The occurrence of GNB in adults is rare, with only 12 well documented cases reported in the English literature. [4][5][6][7][8][9][10][11][12][13][14] We report another case of GNB in a 50-year-old Saudi male.…”

Section: Introductionmentioning

confidence: 99%

Ganglioneuroblastoma in a 50-Year-old Saudi Man: Report of a Case With Review of Literature

Akhtar

Ali

1985

Ann Saudi Med

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“…Various misleading synonyms including the terms neurofibrosarcoma, neurogenic sarcoma, malignant neurilemmoma and malignant schwannoma have previously all been applied to this neoplasm and are merely the expression of the controversial clinicopathologic classification of this rare tumour (Bailet et al, 1991;Wanebo et al, 1993). Malignant schwannoma was first described by Lewis and Hart (1930). The term ''Malignant Peripheral Nerve Sheath Tumour'' has been adopted in the beginning of 1990s, by the World Health Organization Committee for the Classification of Soft Tissue Tumours, after advances in electron microscopy and immunohistochemistry have contributed to the histologic diagnosis of MPNST (Hajdu, 1993;Enzinger and Weiss, 1995).…”

Section: Introductionmentioning

confidence: 99%