Tumors of Childhood in Ibadan, Nigeria (1973-1990)

Akang, E. E. U.

doi:10.1080/15513819609169305

Cited by 11 publications

(4 citation statements)

References 11 publications

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“…In both sexes, haematopoietic, kidney, eye, and soft tissue were the topmost cause of cancer death in the paediatric age. This cancer mortality picture is comparable to the reported cancer morbidity trend in the Ghanaian paediatric population [ 16 ] and other developing African countries [ 17 – 29 ], with a preponderance of Burkitt's lymphomas, followed by retinoblastoma, nephroblastoma, and soft tissue sarcomas. However, low relative frequency of Burkitt lymphoma in our center compared with its higher frequency in other parts of Nigeria and other sub-Saharan African countries has been previously reported by Akinde et al [ 30 ] and Tijani et al [ 27 ].…”

Section: Discussionsupporting

confidence: 83%

Cancer Mortality Pattern in Lagos University Teaching Hospital, Lagos, Nigeria

Akinde

Phillips

Oguntunde

et al. 2015

Journal of Cancer Epidemiology

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Background. Cancer is a leading cause of death worldwide and about 70% of all cancer deaths occurred in low- and middle-income countries. The cancer mortality pattern is quite different in Africa compared to other parts of the world. Extensive literature research showed little or no information about the overall deaths attributable to cancer in Nigeria. Aims and Objectives. This study aims at providing data on the patterns of cancer deaths in our center using the hospital and autopsy death registers. Methodology. Demographic, clinical data of patients who died of cancer were extracted from death registers in the wards and mortuary over a period of 14 years (2000–2013). Results. A total of 1436 (4.74%) cancer deaths out of 30287 deaths recorded during the period. The male to female ratio was 1 : 2.2 and the peak age of death was between 51 and 60 years. Overall, breast cancer was responsible for most of the deaths. Conclusion. The study shows that the cancers that accounted for majority of death occurred in organs that were accessible to screening procedures and not necessary for survival. We advise regular screening for precancerous lesions in these organs so as to reduce the mortality rate and burden of cancer.

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Section: Discussionsupporting

confidence: 83%

Cancer Mortality Pattern in Lagos University Teaching Hospital, Lagos, Nigeria

Akinde

Phillips

Oguntunde

et al. 2015

Journal of Cancer Epidemiology

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“…The study documented a mean annual rate of 9.7 cases per year; and with the exclusion of the leukaemias, it amounted to 8.3 solid malignancies per year. This is higher than the 7 cases per annum reported in Sagamu 17 23 . It is our view that the centres with the highest number of cases were those that were equipped with radiotherapy services, and that the higher figures may have been contributed by referral cases from other centres.…”

Section: Discussioncontrasting

confidence: 54%

Histological pattern and clinical outcome of childhood malignancies in a Nigerian tertiary care centre

Uchendu

Ekpebe²

2021

Sri Lanka J Child Health

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Background: Childhood cancer is an emerging, poorly addressed public health problem in developing countries. Information on the incidence and mortality of childhood cancer is scarce in these countries, despite its relevance in decision making in health sector reforms.Objectives: To describe the histological pattern and clinical outcome of childhood malignancies in a Nigerian tertiary care centre.Method: This is a retrospective study of childhood cancer (<18 years) using the age, gender, histological diagnosis and their clinical outcome from 2014 to 2019 in Delta State University Teaching Hospital (DELSUTH), using information from histopathology records and patient's case notes. Data was analysed with Microsoft Excel spreadsheet and presented in tables Results: Fifty-eight cancer cases were managed from 2014-2019, consisting of 35 males and 23 females with age range and mean age of 8 months to 17.5 years and 7.6 years respectively. The age distribution was as follows: <1years: 1.7%; 1-<5 years 29.3%; 5-<10 years 36.2%; 10-<15 years 24.1% and 15-<18 years 8.6%. The major histological types encountered with their corresponding incidence are nephroblastoma (20.7%), leukaemia (13.8%), yolk sac tumour (10.3%), rhabdomyosarcoma (8.6%), neuroblastoma (6.9%), osteosarcoma (6.9%), retinoblastoma (6.9%), Burkitt lymphoma (5.2%), liver cancer (5.2%), Hodgkin lymphoma (5.2%) _________________________________________

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“…2 Ewing sarcoma is associated with a specific cytogenetic translocation t(11;22)(q24;q12) 13 and is generally uncommon in black African children and almost exclusively limited to Caucasians. 14 Studies from North America and other countries confirm the relatively low incidence of Ewing sarcoma in the black population. 15,16 In this study, all the cases were black Africans.…”

Section: Discussionmentioning

confidence: 94%

Primary Bone Tumors in Children and Adolescents Treated at a Referral Center in Northern Tanzania

2019

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Bone tumors account for a small fraction of childhood cancers. Most published reports are from developed countries. The purpose of this study was to review the primary bone tumors in children and adolescents treated at a referral center in Northern Tanzania. We completed a 10-year hospital-based cross-sectional study in which all patients younger than 20 years diagnosed with a primary bone tumor at the Kilimanjaro Christian Medical Center Orthopaedic Department from January 2006 to December 2015 were identified and reviewed. Of the 80 identified patients, 15 (18.8%) were aged 5 to 8 years, and 65 (81%) were aged 9 to 19 years. Forty-seven males (59%) and 33 females (41%) were identified. The most common tumor locations were the femur, tibia, and humerus. Osteosarcoma was the most common malignant diagnosis (49 patients, 61%). No cases of Ewing sarcoma were reported. The most common tribal origins of the patients were Chagga and Maasai. Most primary bone tumors treated at a referral center in Northern Tanzania are malignant, with osteosarcoma representing the vast majority. No cases of Ewing sarcoma were identified in this tertiary referral hospital–based database.

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Tumors of Childhood in Ibadan, Nigeria (1973-1990)

Cited by 11 publications

References 11 publications

Cancer Mortality Pattern in Lagos University Teaching Hospital, Lagos, Nigeria

Cancer Mortality Pattern in Lagos University Teaching Hospital, Lagos, Nigeria

Histological pattern and clinical outcome of childhood malignancies in a Nigerian tertiary care centre

Primary Bone Tumors in Children and Adolescents Treated at a Referral Center in Northern Tanzania

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