Tumores neuroendócrinos do cólon e reto: experiência do Instituto Nacional do Câncer no Brasil

Abstract

The treatment of colon and rectal NETs is complex, because it depends of the individuality of each patient. With adequate management, the prognosis can be favorable with long survival, but it is related to the tumor differentiation degree, efficacy of the chosen treatment and to the patient adhesion to the follow-up after treatment.

The Effect of Preceding Biopsy on Complete Endoscopic Resection in Rectal Carcinoid Tumor

“…Most rectal carcinoid tumors are small and movable subepithelial lesions located between 4 and 20 cm above the dentate line and are mainly discovered incidentally on routine lower endoscopy (7, 8, 9, 10). Such a small tumor rarely metastasizes and endoscopic resection is curative.…”

Difference in survival between right- versus left-sided colorectal neuroendocrine neoplasms

“…Colorectal NENs are mostly non-functional, and while often presenting similarly to adenocarcinomas, are both pathologically and in terms of their behavior quite distinct (Portale et al, 2012;Cesar et al, 2013). It has long been widely recognized that there are distinct differences in terms of the epidemiology, clinical manifestations and prognosis between rightand left-sided colorectal adenocarcinomas, with the National Comprehensive Cancer Network (NCCN) guidelines (Benson et al, 2017) confirming the significance of the primary tumor location in the treatment of metastatic colorectal cancer (mCRC).…”

Tumor Neuroendócrino Do Canal Anal

“…Em 2000, observou-se que essa neoplasia possuía diferenças morfológicas e biológicas, levando a OMS a aderir uma nova e atualizada classificação alterando sua denominação para tumores neuroendócrinos e carcinomas neuroendócrinos. A distinção ocorria entre os tumores neuroendócrinos bem diferenciados que revelavam, conforme classificação da OMS: a) comportamento benigno ou potencial maligno incerto; b) comportamento benigno com baixo grau de malignidade; c) carcinomas neuroendócrinos bem diferenciados com baixo potencial maligno; d) carcinomas neuroendócrinos pouco diferenciados com alto potencial maligno 3 . optando por fazer ressecção transanal que foi realizada.…”