Tumores de los hemisferios cerebrales en la neurofibromatosis tipo 1 durante la infancia

Pascual-Castroviejo, I; Pascual-Pascual, Samuel Ignacio; Viaño, J.; Velazquez-Fragua, R.; Carceller-Benito, Fernando; Gutiérrez-Molina, M; Morales-Bastos, Carmen

doi:10.33588/rn.5008.2009726

Cited by 3 publications

(1 citation statement)

References 9 publications

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“…La presencia de tumores intracraneales en personas con NF1 es de muy diversa localización. Hay zonas muy predispuestas a presentar tumor, como las vías ópticas -nervios ópticos, quiasma, cintillas y proyecciones posteriores-, que comprenden el 14-15% de los tumores de cualquier localización asociados a NF1 [4][5][6], mientras que otras localizaciones son bastante infrecuentes, como ocurre con los tumores de los hemisferios cerebrales y la fosa posterior (excluyendo el cerebelo), que constituyen el 1 [7] y el 0,83% [8], respectivamente. Los tumores del tronco cerebral se sitúan en prevalencias próximas al 4% [9].…”

Section: Introductionunclassified

Tumor del cuerpo calloso como presentación de neurofibromatosis tipo 1 en un paciente y revisión de la bibliografía

Pascual-Castroviejo

Pascual-Pascual²,

Velazquez-Fragua³

et al. 2012

RevNeurol

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Section: Introductionunclassified

Tumor del cuerpo calloso como presentación de neurofibromatosis tipo 1 en un paciente y revisión de la bibliografía

Pascual-Castroviejo

Pascual-Pascual²,

Velazquez-Fragua³

et al. 2012

RevNeurol

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Involución espontánea de tumores frontales en un paciente con neurofibromatosis tipo 1

Pascual-Castroviejo¹,

Quiñones-Tapia²

2010

RevNeurol

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Potential Use of Long Noncoding RNAs as Biomarkers for Astrocytoma

Esparza‐Garrido¹,

Siordia-Reyes²,

Sánchez³

et al. 2019

Primary Intracranial Tumors

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Noncoding RNAs represent a high proportion of the human genome and regulate gene expression by means of innumerable and unimaginable modes of action. Particularly, long noncoding RNAs have emerged as central regulators of gene expression and alterations on their function have been associated with many types of cancer, such as astrocytomas. Astrocytomas are the most common type of gliomas in the central nervous system, and glioblastoma multiforme is their most aggressive form. Although adult and pediatric astrocytomas exhibit certain molecular similarities, they are considered as distinct molecular entities. Since to date there is no effective treatments for these tumors, different efforts are being made to find molecular tools useful for this purpose. Studies have shown that both tumor and circulating expression of lncRNAs were altered in astrocytoma, which was useful to distinguish the patients with this neoplasia from those without cancer, as well as to determine different prognostic factors related to the disease. According to these studies, different "molecular signatures" of specific lncRNAs were established, and they have a potential use in the medical practice. From a system biological perspective, complex interaction networks, conformed by lncRNAs, microRNAs, mRNAs, and proteins, were elucidated and predicted to control many oncogenic processes.

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Tumores de los hemisferios cerebrales en la neurofibromatosis tipo 1 durante la infancia

Cited by 3 publications

References 9 publications

Tumor del cuerpo calloso como presentación de neurofibromatosis tipo 1 en un paciente y revisión de la bibliografía

Tumor del cuerpo calloso como presentación de neurofibromatosis tipo 1 en un paciente y revisión de la bibliografía

Involución espontánea de tumores frontales en un paciente con neurofibromatosis tipo 1

Potential Use of Long Noncoding RNAs as Biomarkers for Astrocytoma

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