Tumores de la región pineal en la edad pediátrica. Presentación de 23 casos y revisión de la bibliografía

Navas-García, M; Goig-Revert, F; Villarejo-Ortega, Francisco; Robla, J; Prada, Inmaculada de; Madero, Luís; Pérez-Díaz, Cinthia Ivette; Rivero-Martin, M B; Martin-Gamero, A Pascual; Budke, Marcelo; Cordobés-Tapia, F

doi:10.33588/rn.5211.2010616

Cited by 4 publications

(4 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The tumor was in the brain midline, where GN is usually found 1,3 and the patient suffered from common symptoms, such as weight loss, blurred vision, and memory problems. Parinaud's syndrome, caused by compression of the midbrain quadrigeminal lamina was also observed 16 . Because of these neurological symptoms, the patient was admitted for emergency treatment.…”

Section: Discussionmentioning

confidence: 99%

“…Parinaud's syndrome, caused by compression of the midbrain quadrigeminal lamina was also observed. 16 Because of these neurological symptoms, the patient was admitted for emergency treatment. Computed tomography and MRI confirmed the presence of a mass that could explain the symptoms, which were partially relieved by laparoscopic ventricular drainage.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Pineal germinoma in a young adult: A case report

Fernández-Rodríguez

Maldonado

2022

Cancer Reports

View full text Add to dashboard Cite

Background Intracranial germinomas (GN) are rare cancers that primarily affect children, making them rarer still in adults. Standard treatment for this neoplasm includes neoadjuvant chemotherapy (NC) followed by radiotherapy (RT) or RT at a higher dose and larger field. These recommendations are based on studies focused mostly on children; it is currently unclear whether this treatment is applicable to adults. Case We present a case of a 23‐year‐old adult male with no underlying pathologies, drug allergies, or family history of cancer, who presented for medical evaluation with blurred vision, diplopia, forgetfulness, and weight loss starting 3–4 months before the evaluation. Clinical examination indicated Parinaud's Syndrome. Magnetic resonance imaging (MRI) and computed tomography (CT) revealed a pineal tumor with ependymal dissemination in both lateral ventricles, which was causing obstructive hydrocephalus. The patient had surgery consisting of ventriculostomy, Holter shunt insertion, cisternal ventricular intubation, and cisterna magna anastomosis to improve ventricular drainage. Pathology confirmed pineal germinoma. Cerebrospinal fluid cytology and MRI of the axis were negative. Four cycles of NC were given to the patient (carboplatin, etoposide, and ifosfamide), with reduced dosage. Once a partial volumetric response was confirmed, whole‐ventricular radiotherapy (WVR) was initiated with a total tumor bed dose of 45 Gy over 25 sessions in 5 weeks. Optimum clinical results were observed, and no short‐term (<90 day) radiation toxicity was observed. The patient was able to resume his normal activities soon after treatment. Follow‐ups over 2 years post‐surgery indicated continued control of the lesion and absence of symptoms except for mild diplopia. Conclusion Although this is a case report, these data suggest that a reduced NC course and WVR may effectively treat adult GN. This protocol likely decreases the risk of undesirable NC and RT secondary effects, while providing excellent local control; however, using a narrower RT field is not recommended.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Pineal germinoma in a young adult: A case report

Fernández-Rodríguez

Maldonado

2022

Cancer Reports

View full text Add to dashboard Cite

show abstract

“…un predominio en varones en aproximadamente dos veces más que las mujeres de desarrollar tumores de células germinales 1,2,3 . Las localizaciones más frecuentes, predominan en la línea media a nivel pineal y supraselar 1,2 .…”

Section: Existeunclassified

Tumores germinales del sistema nervioso central: Características epidemiológicas y sobrevida en niños, hospital nacional Edgardo Rebagliati Martins - Essalud, 1999 2017

2018

RFMH

View full text Add to dashboard Cite

show abstract

“…La policitemia tiene una relativa incidencia en 1-5% de todos los nacidos vivos; tiene relación con diversos factores como la talla y peso al nacimiento, corte tardío del cordón umbilical, entre otros (9)(10)(11)(12), por lo que resulta de trascendental importancia conocer sobre esta patología, considerando las complicaciones que puede ocasionar (enterocolitis necrotizante, convulsiones, hipocalcemia e hipoglicemia, trombocitopenia, irritabilidad) (13).…”

Section: Introductionunclassified

Factores de riesgo del neonato asociados a la Policitemia

León- Pacheco,

Villavicencio Pazmiño,

Cueva Calle

et al. 2022

Salud

View full text Add to dashboard Cite

El objetivo del manuscrito es describir la relación existente entre la policitemia y los factores de riesgo que presentan los neonatos para su presentación. La investigación es cuantitativa, descriptiva, analítica y transversal. Se revisó un total de 1669 historias clínicas de recién nacidos, entre enero 2014 y diciembre 2015, registradas en una casa de salud pública de segundo nivel de atención, el cual, presta sus servicios a las provincias de la Zona 6 del Ecuador (Azuay, Cañar y Morona Santiago). Los resultados indican que existen factores de riesgo del neonato para desarrollar policitemia. Se concluye que los factores “bajo peso al nacer”, “recién nacido pequeño para la edad gestacional”, “la asfixia perinatal” y factores maternos como los “antecedentes de preeclampcia” están relacionados de manera significativa con la policitemia neonatal.

show abstract

Tumores de la región pineal en la edad pediátrica. Presentación de 23 casos y revisión de la bibliografía

Abstract: Conclusions. The study of tumour markers can be used to guide the diagnosis of certain tumours of the pineal region. At present, the recommended procedure involves taking a histological sample of the tumour in order to establish an accurate diagnosis and a specific oncological treatment.

Cited by 4 publications

References 32 publications

Pineal germinoma in a young adult: A case report

Pineal germinoma in a young adult: A case report

Tumores germinales del sistema nervioso central: Características epidemiológicas y sobrevida en niños, hospital nacional Edgardo Rebagliati Martins - Essalud, 1999 2017

Factores de riesgo del neonato asociados a la Policitemia

Contact Info

Product

Resources

About